A. nidulans fksA/AN3729 Summary

Summary

Locus History

fksA BASIC INFORMATION [ View References ]

Standard Name

fksA¹

Systematic Name, Reference Strain

AN3729 (A. nidulans FGSC A4)

Alias

ANID_03729, ANIA_03729

Feature Type

ORF, Verified

Description

Putative 1,3-beta-glucan synthase with a predicted role in glucan biosynthesis (2)

Literature

Orthologous genes in Aspergillus species

A. oryzae RIB40 Ortholog(s) : AO090009000174/fks1
A. fumigatus Af293 Ortholog(s) : Afu6g12400/fks1
A. niger CBS 513.88 Ortholog(s) : An06g01550/fksA
View ortholog cluster : 21 genes among 21 Aspergillus-related species/strains
View alignment

Ortholog(s) in non-AspGD species

N. crassa (do) ; C. albicans (GSC1) ; S. pombe (bgs4) ; S. cerevisiae (FKS1)

Chromosomal Location

GBrowse for A. nidulans FGSC A4
Click on map for expanded view
AN3729

GO Annotations		View all fksA GO evidence and references
Molecular Function
Manually curated		1,3-beta-D-glucan synthase activity (ISA with S. cerevisiae: GSC2, S. cerevisiae: FKS1, IDA)
Computational		1,3-beta-D-glucan synthase activity (RCA)
Biological Process
Manually curated		(1->3)-beta-D-glucan biosynthetic process (ISA with S. cerevisiae: GSC2, S. cerevisiae: FKS1, IDA)
Computational		cellular response to drug (IEA with C. albicans: GSC1, A. fumigatus: fks1) establishment of mitotic actomyosin contractile ring localization (IEA with S. pombe: bgs4) fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process (IEA with S. pombe: bgs4) fungal-type cell wall organization (IEA with C. albicans: GSC1) glucan biosynthetic process (RCA) pathogenesis (IEA with C. albicans: GSC1) positive regulation of endocytosis (IEA with S. cerevisiae: FKS1) primary cell septum biogenesis (IEA with S. pombe: bgs4) regulation of cell size (IEA with S. cerevisiae: FKS1)
Cellular Component
Manually curated		1,3-beta-D-glucan synthase complex (ISS, IDA) membrane (IDA)
Computational		actin cortical patch (IEA with S. cerevisiae: FKS1) actomyosin contractile ring (IEA with S. pombe: bgs4) barrier septum (IEA with S. pombe: bgs4) cellular bud neck (IEA with S. cerevisiae: FKS1) cellular bud tip (IEA with S. cerevisiae: FKS1) endoplasmic reticulum (IEA with S. pombe: bgs4) hyphal tip (IEA with A. fumigatus: fks1) mating projection tip (IEA with S. pombe: bgs4) mitochondrion (IEA with S. cerevisiae: FKS1) new growing cell tip (IEA with S. pombe: bgs4) plasma membrane of cell tip (IEA with S. pombe: bgs4) primary cell septum (IEA with S. pombe: bgs4)

Sequence Information

ChrII_A_nidulans_FGSC_A4:3255844 to 3261673 | GBrowse

Last Update

Coordinates: 2011-12-16 | Sequence: 2009-03-02

Subfeature Details

	Relative Coordinates			Chromosomal Coordinates			Most Recent Update
	Relative Coordinates			Chromosomal Coordinates			Coordinates	Sequence
5' UTR	-633	to	-86	3,255,211	to	3,255,758	2013-01-24	2013-01-24
5' UTR intron	-85	to	-29	3,255,759	to	3,255,815	2013-01-24	2013-01-24
5' UTR	-28	to	-1	3,255,816	to	3,255,843	2013-01-24	2013-01-24
CDS	1	to	158	3,255,844	to	3,256,001	2011-12-16	2009-03-02
Intron	159	to	214	3,256,002	to	3,256,057	2011-12-16	2009-03-02
CDS	215	to	5473	3,256,058	to	3,261,316	2011-12-16	2009-03-02
Intron	5474	to	5529	3,261,317	to	3,261,372	2011-12-16	2009-03-02
CDS	5530	to	5830	3,261,373	to	3,261,673	2011-12-16	2009-03-02
3' UTR	5831	to	6218	3,261,674	to	3,262,061	2012-08-30	2012-08-30

Retrieve Sequences
Sequence Analysis Tools
Maps & Displays

RNA-Seq Data

External Links

Primary AspGDID

ASPL0000011003

ADDITIONAL INFORMATION for fksA

Locus History

Gene/Sequence Resources

LOCUS SUMMARY NOTES for fksA

Description from CADRE : hypothetical protein similar to 1,3-beta-D-glucan synthase catalytic subunit

GO terms assigned by Eurofung/TIGR:
- 1,3-beta-glucan synthase activity (GO:0003843), ISS, with NCBI_gi:1491929, PMID:8755864, Assigned by: TIGR
- 1,3-beta-glucan synthase activity (GO:0003843), ISS, with Pfam:PF02364, Assigned by: TIGR
- 1,3-beta-glucan synthase complex (GO:0000148), ISS, with NCBI_gi:1491929, PMID:8755864, Assigned by: TIGR
- membrane (GO:0016020), ISS, with Pfam:PF02364, Assigned by: TIGR
- 1,3-beta-glucan biosynthetic process (GO:0006075), ISS, with NCBI_gi:1491929, PMID:8755864, Assigned by: TIGR
- 1,3-beta-glucan biosynthetic process (GO:0006075), ISS, with Pfam:PF02364, Assigned by: TIGR

Last Updated: 2010-07-06

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for fksA]

1)	*Kelly R, et al.* (1996)** Isolation of a gene involved in 1,3-beta-glucan synthesis in Aspergillus nidulans and purification of the corresponding protein. J Bacteriol 178(15):4381-91
2)	*David H, et al.* (2008)** Analysis of Aspergillus nidulans metabolism at the genome-scale. BMC Genomics 9:163

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