A. fumigatus wetA/Afu4g13230 Summary

Summary

Locus History

wetA BASIC INFORMATION [ View References ]

Standard Name

wetA¹

Systematic Name, Reference Strain

Afu4g13230 (A. fumigatus Af293)

Alias

AFUA_4G13230, CADAFUAG00007811²

Systematic Names Used in Other Strains

AFUB_070140 (A. fumigatus A1163)

Feature Type

ORF, Verified

Description

Ortholog of A. nidulans WetA, a developmental regulatory protein involved in conidial development and activator of conidium-specific gene expression; essential for trehalose biogenesis in conidia (1, 3)

Literature

Orthologous genes in Aspergillus species

A. oryzae RIB40 Ortholog(s) : AO090009000260
A. nidulans FGSC A4 Ortholog(s) : AN1937/wetA
A. niger CBS 513.88 Ortholog(s) : An01g08900/wetA
View ortholog cluster : 22 genes among 21 Aspergillus-related species/strains
View alignment

Best hit(s) in non-AspGD species

N. crassa (NCU01033)

Chromosomal Location

GBrowse for A. fumigatus Af293
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Afu4g13230

GO Annotations		View all wetA GO evidence and references
Molecular Function
Manually curated		molecular_function unknown (ND)
Biological Process
Manually curated		asexual spore wall assembly (IMP) trehalose biosynthetic process (IMP)
Computational		conidium formation (IEA with A. nidulans: wetA) pigment biosynthetic process (IEA with A. nidulans: wetA) positive regulation of conidium formation (IEA with A. nidulans: wetA) positive regulation of transcription from RNA polymerase II promoter (IEA with A. nidulans: wetA)
Cellular Component
Manually curated		cellular_component unknown (ND)

Mutant Phenotype		View all wetA Phenotype details and references
Classical genetics
null		vosA mRNA accumulation: decreased conidial germination: delayed conidiation: decreased hyphal growth: abnormal viability: decreased viable

Sequence Information

Chr4_A_fumigatus_Af293:3465687 to 3467387 | GBrowse

Last Update

Coordinates: 2012-03-06 | Sequence: 2011-01-08

Subfeature Details

		Relative Coordinates				Chromosomal Coordinates				Most Recent Update
		Relative Coordinates				Chromosomal Coordinates				Coordinates		Sequence
CDS		1	to	1701		3,465,687	to	3,467,387		2012-03-06		2011-01-08

Retrieve Sequences
Sequence Analysis Tools
Maps & Displays

RNA-Seq Data

Sequence Variation

External Links

CADRE | FungiDB | GenBank (1, 2, 3, 4) | SwissProt

Primary AspGDID

ASPL0000107029

ADDITIONAL INFORMATION for wetA

Locus History

Gene/Sequence Resources

LOCUS SUMMARY NOTES for wetA

Name listed in the Broad Institute genome_summary_per_gene_file: regulatory protein weta

Last Updated: 2010-08-25

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for wetA]

1)	*Lamarre C, et al.* (2008)** Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia. BMC Genomics 9:417
2)	AspGD (2012) Update of Aspergillus fumigatus Af293 reference annotation
3)	Tao L and Yu JH (2011) AbaA and WetA govern distinct stages of Aspergillus fumigatus development. Microbiology 157(Pt 2):313-26

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