A. niger An03g01010 Summary

Summary

Locus History

An03g01010 BASIC INFORMATION [ View References ]

Systematic Name, Reference Strain

An03g01010 (A. niger CBS 513.88)

Systematic Names Used in Other Strains

55493-mRNA (A. niger ATCC 1015), 47817-mRNA (A. niger ATCC 1015), 55133-mRNA (A. niger ATCC 1015)

Feature Type

ORF, Uncharacterized

Description

Sedolisin family secreted protease; lysosomal pepstatin-insensitive protease (1, 2)

Orthologous genes in Aspergillus species

A. oryzae RIB40 Ortholog(s) : AO090023000263, AO090026000083
A. fumigatus Af293 Ortholog(s) : Afu6g10250/aorO
A. nidulans FGSC A4 Ortholog(s) : AN7201
A. niger CBS 513.88 Ortholog(s) : An01g01750, An11g01110
View ortholog cluster : 38 genes among 21 Aspergillus-related species/strains
View alignment

Best hit(s) in non-AspGD species

N. crassa (NCU08418)

Chromosomal Location

GBrowse for A. niger CBS 513.88
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An03g01010

GO Annotations		View all An03g01010 GO evidence and references
Molecular Function
Computational		serine-type endopeptidase activity (IEA with EBI: IPR000209)
Biological Process
Computational		proteolysis (IEA with A. fumigatus: aorO)
Cellular Component
Manually curated		cellular_component unknown (ND)

Sequence Information

An03_A_niger_CBS_513_88:199640 to 197246 | GBrowse
Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2011-08-18 | Sequence: 2011-08-18

Subfeature Details

	Relative Coordinates			Chromosomal Coordinates			Most Recent Update
	Relative Coordinates			Chromosomal Coordinates			Coordinates	Sequence
5' UTR	-154	to	-1	199,794	to	199,641	2013-07-30	2013-07-30
CDS	1	to	212	199,640	to	199,429	2011-08-18	2011-08-18
Intron	213	to	303	199,428	to	199,338	2011-08-18	2011-08-18
CDS	304	to	567	199,337	to	199,074	2011-08-18	2011-08-18
Intron	568	to	619	199,073	to	199,022	2011-08-18	2011-08-18
CDS	620	to	1081	199,021	to	198,560	2011-08-18	2011-08-18
Intron	1082	to	1130	198,559	to	198,511	2011-08-18	2011-08-18
CDS	1131	to	1248	198,510	to	198,393	2011-08-18	2011-08-18
Intron	1249	to	1294	198,392	to	198,347	2011-08-18	2011-08-18
CDS	1295	to	1385	198,346	to	198,256	2011-08-18	2011-08-18
Intron	1386	to	1438	198,255	to	198,203	2011-08-18	2011-08-18
CDS	1439	to	2070	198,202	to	197,571	2011-08-18	2011-08-18
Intron	2071	to	2124	197,570	to	197,517	2011-08-18	2011-08-18
CDS	2125	to	2267	197,516	to	197,374	2011-08-18	2011-08-18
Intron	2268	to	2322	197,373	to	197,319	2011-08-18	2011-08-18
CDS	2323	to	2395	197,318	to	197,246	2011-08-18	2011-08-18
3' UTR	2396	to	2632	197,245	to	197,009	2013-07-30	2013-07-30

Retrieve Sequences
Sequence Analysis Tools
Maps & Displays

RNA-Seq Data

External Links

FungiDB | GenBank (1, 2) | TrEMBL

Primary AspGDID

ASPL0000193303

ADDITIONAL INFORMATION for An03g01010

Locus History

Gene/Sequence Resources

LOCUS SUMMARY NOTES for An03g01010

Information from the GenBank record :

db_xref = GI:134057676
inference = profile:COGS:COG4934
protein_id = CAK38074.1
note = unnamed protein product; Catalytic activity: CLN2 of H. sapiens releases an N-terminal tripeptide from a polypeptide.; Remark: a partial protein sequence of CLN2 of H. sapiens, described as lung cancer associated polypeptide sequence SEQ ID 618, is covered by patent WO200055180-A2 (AC# AAB58280).; Remark: defects in CLN2 are the cause of classical late-infantile neuronal ceroid lipofuscinosis (lincl) (also known as ceroid lipofuscinosis neuronal 2; cln2).; Similarity: the predicted A. niger protein shows similarity to the lysosomal pepstatin insensitive protease (CLN2) of H. sapiens and other mammalians, which belong to the peptidase family S53.; Title: strong similarity to lysosomal pepstatin insensitive protease CLN2 - Homo sapiens

Last Updated: 2011-08-19

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for An03g01010]

1)	*Braaksma M, et al.* (2010)** An inventory of the Aspergillus niger secretome by combining in silico predictions with shotgun proteomics data. BMC Genomics 11:584
2)	*Nitsche BM, et al.* (2012)** The carbon starvation response of Aspergillus niger during submerged cultivation: insights from the transcriptome and secretome. BMC Genomics 13:380

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