These related phenotype terms may also be of interest: endomembrane system morphology .
These related phenotype terms may also be of interest: endomembrane system morphology .
| 14 Single Mutant Phenotype(s) for vacuolar morphology | |||||||
|---|---|---|---|---|---|---|---|
| Gene Name | Organism | Experiment type | Mutant Information | Phenotype | Details | References | All phenotypes |
| avaB/AN10849 | A. nidulans | classical genetics | Description: null Allele: avaB::argB |
vacuolar morphology: abnormal | Details: fragmented vacuoles |
Oka M, et al. (2004) Molecular cloning and functional characterization of avaB, a gene encoding Vam6p/Vps39p-like protein in Aspergillus nidulans. FEMS Microbiol Lett 232(1):113-21 | avaB phenotypes |
| bemA/AN7030 | A. nidulans | classical genetics | Description: null Allele: bemA::argB (A. fumigatus argB marker) |
vacuolar morphology: abnormal | Details: fragmented vacuoles |
Leeder AC and Turner G (2008) Characterisation of Aspergillus nidulans polarisome component BemA. Fungal Genet Biol 45(6):897-911 | bemA phenotypes |
| digA/AN2266 | A. nidulans | classical genetics | Description: unspecified Allele: G3162A |
vacuolar morphology: abnormal | Details: Fragmented vacuoles, alkaline phosphatase misdistribution |
Geissenhoner A, et al. (2001) Aspergillus nidulans DigA, a potential homolog of Saccharomyces cerevisiae Pep3 (Vps18), is required for nuclear migration, mitochondrial morphology and polarized growth. Mol Genet Genomics 266(4):672-85 | digA phenotypes |
| pmcA/AN1189 | A. nidulans | classical genetics | Description: null Allele: pmcA::pyroA |
vacuolar morphology: abnormal | Details: fragmented vacuoles |
Findon H, et al. (2010) Analysis of a novel calcium auxotrophy in Aspergillus nidulans. Fungal Genet Biol 47(7):647-55 | pmcA phenotypes |
| pmcB/AN4920 | A. nidulans | classical genetics | Description: null Allele: pmcB::pabaA |
vacuolar morphology: abnormal | Details: fragmented vacuoles |
Findon H, et al. (2010) Analysis of a novel calcium auxotrophy in Aspergillus nidulans. Fungal Genet Biol 47(7):647-55 | pmcB phenotypes |
| rabA/AN4915 | A. nidulans | classical genetics | Description: null | vacuolar morphology: abnormal | Details: atypically small vacuoles |
Abenza JF, et al. (2010) Aspergillus RabB Rab5 integrates acquisition of degradative identity with the long distance movement of early endosomes. Mol Biol Cell 21(15):2756-69 | rabA phenotypes |
| rabB/AN3842 | A. nidulans | classical genetics | Description: null | vacuolar morphology: abnormal | Details: atypically small vacuoles |
Abenza JF, et al. (2010) Aspergillus RabB Rab5 integrates acquisition of degradative identity with the long distance movement of early endosomes. Mol Biol Cell 21(15):2756-69 | rabB phenotypes |
| rabC/AN7602 | A. nidulans | classical genetics | Description: null Allele: srgC[rabC::AfpyrG] |
vacuolar morphology: abnormal | Details: vacuolar fragmentation observed |
Pantazopoulou A and Penalva MA (2011) Characterization of Aspergillus nidulans RabC/Rab6. Traffic 12(4):386-406 | rabC phenotypes |
| rabS/AN0089 | A. nidulans | classical genetics | Description: null Allele: avaA::argB |
vacuolar morphology: abnormal | Details: highly fragmented vacuoles |
Ohsumi K, et al. (2002) Cloning and characterization of a gene (avaA) from Aspergillus nidulans encoding a small GTPase involved in vacuolar biogenesis. Gene 291(1-2):77-84 | rabS phenotypes |
| sltA/AN2919 | A. nidulans | classical genetics | Description: null Allele: sltA::riboBf |
vacuolar morphology: abnormal | Details: enlarged vacuoles |
Findon H, et al. (2010) Analysis of a novel calcium auxotrophy in Aspergillus nidulans. Fungal Genet Biol 47(7):647-55 | sltA phenotypes |
| vpsA/AN8023 | A. nidulans | classical genetics | Description: null Allele: vpsA::argB |
vacuolar morphology: abnormal | Tarutani Y, et al. (2001) Cloning and characterization of Aspergillus nidulans vpsA gene which is involved in vacuolar biogenesis. Gene 268(1-2):23-30 | vpsA phenotypes | |
| rasA/Afu5g11230 | A. fumigatus | classical genetics | Description: activation Allele: rasA (G17V) |
vacuolar morphology: abnormal | Details: abberant vacuolar accumulation and expansion |
Fortwendel JR, et al. (2011) Regulatable Ras activity is critical for proper establishment and maintenance of polarity in Aspergillus fumigatus. Eukaryot Cell 10(4):611-5 | rasA phenotypes |
| vps2/AO090120000485 | A. oryzae | classical genetics | Description: null | vacuolar morphology: abnormal | Tatsumi A, et al. (2007) Aggregation of endosomal-vacuolar compartments in the Aovps24-deleted strain in the filamentous fungus Aspergillus oryzae. Biochem Biophys Res Commun 362(2):474-9 | vps2 phenotypes | |
| vps24/AO090113000079 | A. oryzae | classical genetics | Description: null Allele: vps24::adeA |
vacuolar morphology: abnormal | Details: normal vacuoles were not observed in mutant strain expressing CPY-EGFP |
Tatsumi A, et al. (2006) Aovps24, a homologue of VPS24, is required for vacuolar formation which could maintain proper growth and development in the filamentous fungus Aspergillus oryzae. Biochem Biophys Res Commun 347(4):970-8 | vps24 phenotypes |
| Analyze gene list: further analyze the gene list displayed above or download information for this list | ||||
| Further Analysis: | Find common features of genes in list | Sort genes into broad categories | View all GO terms used to describe genes in list | |
|---|---|---|---|---|
| Download: | Download All Search Results Download data for the entire gene list in a tab-delimited file | Download selected information for entire gene list. Available information types include Sequence, Coordinates, Chromosomal Feature information, GO annotations, Phenotypes, and Ortholog or Best Hit. | ||
Curation of mutant phenotypes is an ongoing project at AspGD. Please contact AspGD curators to let us know of additional phenotype information that should be incorporated.
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