AspGD Curated Papers

Author(s)	Citation
Zheng H, Kim J, Liew M, Yan JK, Herrera O, Bok JW, Kelleher NL, Keller NP, Wang Y	*Zheng H, et al.* (2015)** Redox metabolites signal polymicrobial biofilm development via the NapA oxidative stress cascade in Aspergillus. Curr Biol 25(1):29-37
Bok JW, Ye R, Clevenger KD, Mead D, Wagner M, Krerowicz A, Albright JC, Goering AW, Thomas PM, Kelleher NL, Keller NP, Wu CC	*Bok JW, et al.* (2015)** Fungal artificial chromosomes for mining of the fungal secondary metabolome. BMC Genomics 16:343
Wiemann P, Lechner BE, Baccile JA, Velk TA, Yin WB, Bok JW, Pakala S, Losada L, Nierman WC, Schroeder FC, Haas H, Keller NP	*Wiemann P, et al.* (2014)** Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus. Front Microbiol 5:530
Bok JW, Wiemann P, Garvey GS, Lim FY, Haas B, Wortman J, Keller NP	*Bok JW, et al.* (2014)** Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus. BMC Genomics 15:1011
Yin WB, Baccile JA, Bok JW, Chen Y, Keller NP, Schroeder FC	*Yin WB, et al.* (2013)** A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus. J Am Chem Soc 135(6):2064-7
Sekonyela R, Palmer JM, Bok JW, Jain S, Berthier E, Forseth R, Schroeder F, Keller NP	*Sekonyela R, et al.* (2013)** RsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis. PLoS One 8(5):e62591
Palmer JM, Bok JW, Lee S, Dagenais TR, Andes DR, Kontoyiannis DP, Keller NP	*Palmer JM, et al.* (2013)** Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus. PeerJ 1:e4
Karimi-Aghcheh R, Bok JW, Phatale PA, Smith KM, Baker SE, Lichius A, Omann M, Zeilinger S, Seiboth B, Rhee C, Keller NP, Freitag M, Kubicek CP	*Karimi-Aghcheh R, et al.* (2013)** Functional analyses of Trichoderma reesei LAE1 reveal conserved and contrasting roles of this regulator. G3 (Bethesda) 3(2):369-78
Bok JW, Soukup AA, Chadwick E, Chiang YM, Wang CC, Keller NP	*Bok JW, et al.* (2013)** VeA and MvlA repression of the cryptic orsellinic acid gene cluster in Aspergillus nidulans involves histone 3 acetylation. Mol Microbiol 89(5):963-74
Yin W, Amaike S, Wohlbach DJ, Gasch AP, Chiang YM, Wang CC, Bok J, Rohlfs M, Keller NP	*Yin WB, et al.* (2012)** An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR. Mol Microbiol 83(5):1024-34
Soukup AA, Chiang YM, Bok JW, Reyes-Dominguez Y, Oakley BR, Wang CC, Strauss J, Keller NP	*Soukup AA, et al.* (2012)** Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production. Mol Microbiol 86(2):314-30
Wiemann P, Brown DW, Kleigrewe K, Bok JW, Keller NP, Humpf HU, Tudzynski B	*Wiemann P, et al.* (2010)** FfVel1 and FfLae1, components of a velvet-like complex in Fusarium fujikuroi, affect differentiation, secondary metabolism and virulence. Mol Microbiol 77(4):972-94
Shaaban MI, Bok JW, Lauer C, Keller NP	*Shaaban MI, et al.* (2010)** Suppressor mutagenesis identifies a velvet complex remediator of Aspergillus nidulans secondary metabolism. Eukaryot Cell 9(12):1816-24
Reyes-Dominguez Y, Bok JW, Berger H, Shwab EK, Basheer A, Gallmetzer A, Scazzocchio C, Keller N, Strauss J	*Reyes-Dominguez Y, et al.* (2010)** Heterochromatic marks are associated with the repression of secondary metabolism clusters in Aspergillus nidulans. Mol Microbiol 76(6):1376-86
Bok JW, Chiang YM, Szewczyk E, Reyes-Dominguez Y, Davidson AD, Sanchez JF, Lo HC, Watanabe K, Strauss J, Oakley BR, Wang CC, Keller NP	*Bok JW, et al.* (2009)** Chromatin-level regulation of biosynthetic gene clusters. Nat Chem Biol 5(7):462-4
Kale SP, Milde L, Trapp MK, Frisvad JC, Keller NP, Bok JW	*Kale SP, et al.* (2008)** Requirement of LaeA for secondary metabolism and sclerotial production in Aspergillus flavus. Fungal Genet Biol 45(10):1422-9
Hammond TM, Bok JW, Andrewski MD, Reyes-Dominguez Y, Scazzocchio C, Keller NP	*Hammond TM, et al.* (2008)** RNA silencing gene truncation in the filamentous fungus Aspergillus nidulans. Eukaryot Cell 7(2):339-49
Bayram O, Krappmann S, Ni M, Bok JW, Helmstaedt K, Valerius O, Braus-Stromeyer S, Kwon NJ, Keller NP, Yu JH, Braus GH	*Bayram O, et al.* (2008)** VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism. Science 320(5882):1504-6
Shwab EK, Bok JW, Tribus M, Galehr J, Graessle S, Keller NP	*Shwab EK, et al.* (2007)** Histone deacetylase activity regulates chemical diversity in Aspergillus. Eukaryot Cell 6(9):1656-64
Perrin RM, Fedorova ND, Bok JW, Cramer RA, Wortman JR, Kim HS, Nierman WC, Keller NP	*Perrin RM, et al.* (2007)** Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA. PLoS Pathog 3(4):e50
Bok JW, Noordermeer D, Kale SP, Keller NP	*Bok JW, et al.* (2006)** Secondary metabolic gene cluster silencing in Aspergillus nidulans. Mol Microbiol 61(6):1636-45
Bok JW, Chung D, Balajee SA, Marr KA, Andes D, Nielsen KF, Frisvad JC, Kirby KA, Keller NP	*Bok JW, et al.* (2006)** GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence. Infect Immun 74(12):6761-8
Bok JW, Hoffmeister D, Maggio-Hall LA, Murillo R, Glasner JD, Keller NP	*Bok JW, et al.* (2006)** Genomic mining for Aspergillus natural products. Chem Biol 13(1):31-7
Tsitsigiannis DI, Bok JW, Andes D, Nielsen KF, Frisvad JC, Keller NP	*Tsitsigiannis DI, et al.* (2005)** Aspergillus cyclooxygenase-like enzymes are associated with prostaglandin production and virulence. Infect Immun 73(8):4548-59
Bok JW, Balajee SA, Marr KA, Andes D, Nielsen KF, Frisvad JC, Keller NP	*Bok JW, et al.* (2005)** LaeA, a regulator of morphogenetic fungal virulence factors. Eukaryot Cell 4(9):1574-82
Calvo AM, Bok J, Brooks W, Keller NP	*Calvo AM, et al.* (2004)** veA is required for toxin and sclerotial production in Aspergillus parasiticus. Appl Environ Microbiol 70(8):4733-9
Bok JW, Keller NP	Bok JW and Keller NP (2004) LaeA, a regulator of secondary metabolism in Aspergillus spp. Eukaryot Cell 3(2):527-35
Jin Y, Bok JW, Guzman-de-Pena D, Keller NP	*Jin Y, et al.* (2002)** Requirement of spermidine for developmental transitions in Aspergillus nidulans. Mol Microbiol 46(3):801-12
Calvo AM, Wilson RA, Bok JW, Keller NP	*Calvo AM, et al.* (2002)** Relationship between secondary metabolism and fungal development. Microbiol Mol Biol Rev 66(3):447-59, table of contents

Author(s)

Citation

Zheng H, Kim J, Liew M, Yan JK, Herrera O, Bok JW, Kelleher NL, Keller NP, Wang Y

Zheng H, et al. (2015) Redox metabolites signal polymicrobial biofilm development via the NapA oxidative stress cascade in Aspergillus. Curr Biol 25(1):29-37

Bok JW, Ye R, Clevenger KD, Mead D, Wagner M, Krerowicz A, Albright JC, Goering AW, Thomas PM, Kelleher NL, Keller NP, Wu CC

Bok JW, et al. (2015) Fungal artificial chromosomes for mining of the fungal secondary metabolome. BMC Genomics 16:343

Wiemann P, Lechner BE, Baccile JA, Velk TA, Yin WB, Bok JW, Pakala S, Losada L, Nierman WC, Schroeder FC, Haas H, Keller NP

Wiemann P, et al. (2014) Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus. Front Microbiol 5:530

Bok JW, Wiemann P, Garvey GS, Lim FY, Haas B, Wortman J, Keller NP

Bok JW, et al. (2014) Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus. BMC Genomics 15:1011

Yin WB, Baccile JA, Bok JW, Chen Y, Keller NP, Schroeder FC

Yin WB, et al. (2013) A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus. J Am Chem Soc 135(6):2064-7

Sekonyela R, Palmer JM, Bok JW, Jain S, Berthier E, Forseth R, Schroeder F, Keller NP

Sekonyela R, et al. (2013) RsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis. PLoS One 8(5):e62591

Palmer JM, Bok JW, Lee S, Dagenais TR, Andes DR, Kontoyiannis DP, Keller NP

Palmer JM, et al. (2013) Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus. PeerJ 1:e4

Karimi-Aghcheh R, Bok JW, Phatale PA, Smith KM, Baker SE, Lichius A, Omann M, Zeilinger S, Seiboth B, Rhee C, Keller NP, Freitag M, Kubicek CP

Karimi-Aghcheh R, et al. (2013) Functional analyses of Trichoderma reesei LAE1 reveal conserved and contrasting roles of this regulator. G3 (Bethesda) 3(2):369-78

Bok JW, Soukup AA, Chadwick E, Chiang YM, Wang CC, Keller NP

Bok JW, et al. (2013) VeA and MvlA repression of the cryptic orsellinic acid gene cluster in Aspergillus nidulans involves histone 3 acetylation. Mol Microbiol 89(5):963-74

Yin W, Amaike S, Wohlbach DJ, Gasch AP, Chiang YM, Wang CC, Bok J, Rohlfs M, Keller NP

Yin WB, et al. (2012) An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR. Mol Microbiol 83(5):1024-34

Soukup AA, Chiang YM, Bok JW, Reyes-Dominguez Y, Oakley BR, Wang CC, Strauss J, Keller NP

Soukup AA, et al. (2012) Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production. Mol Microbiol 86(2):314-30

Wiemann P, Brown DW, Kleigrewe K, Bok JW, Keller NP, Humpf HU, Tudzynski B

Wiemann P, et al. (2010) FfVel1 and FfLae1, components of a velvet-like complex in Fusarium fujikuroi, affect differentiation, secondary metabolism and virulence. Mol Microbiol 77(4):972-94

Shaaban MI, Bok JW, Lauer C, Keller NP

Shaaban MI, et al. (2010) Suppressor mutagenesis identifies a velvet complex remediator of Aspergillus nidulans secondary metabolism. Eukaryot Cell 9(12):1816-24

Reyes-Dominguez Y, Bok JW, Berger H, Shwab EK, Basheer A, Gallmetzer A, Scazzocchio C, Keller N, Strauss J

Reyes-Dominguez Y, et al. (2010) Heterochromatic marks are associated with the repression of secondary metabolism clusters in Aspergillus nidulans. Mol Microbiol 76(6):1376-86

Bok JW, Chiang YM, Szewczyk E, Reyes-Dominguez Y, Davidson AD, Sanchez JF, Lo HC, Watanabe K, Strauss J, Oakley BR, Wang CC, Keller NP

Bok JW, et al. (2009) Chromatin-level regulation of biosynthetic gene clusters. Nat Chem Biol 5(7):462-4

Kale SP, Milde L, Trapp MK, Frisvad JC, Keller NP, Bok JW

Kale SP, et al. (2008) Requirement of LaeA for secondary metabolism and sclerotial production in Aspergillus flavus. Fungal Genet Biol 45(10):1422-9

Hammond TM, Bok JW, Andrewski MD, Reyes-Dominguez Y, Scazzocchio C, Keller NP

Hammond TM, et al. (2008) RNA silencing gene truncation in the filamentous fungus Aspergillus nidulans. Eukaryot Cell 7(2):339-49

Bayram O, Krappmann S, Ni M, Bok JW, Helmstaedt K, Valerius O, Braus-Stromeyer S, Kwon NJ, Keller NP, Yu JH, Braus GH

Bayram O, et al. (2008) VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism. Science 320(5882):1504-6

Shwab EK, Bok JW, Tribus M, Galehr J, Graessle S, Keller NP

Shwab EK, et al. (2007) Histone deacetylase activity regulates chemical diversity in Aspergillus. Eukaryot Cell 6(9):1656-64

Perrin RM, Fedorova ND, Bok JW, Cramer RA, Wortman JR, Kim HS, Nierman WC, Keller NP

Perrin RM, et al. (2007) Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA. PLoS Pathog 3(4):e50

Bok JW, Noordermeer D, Kale SP, Keller NP

Bok JW, et al. (2006) Secondary metabolic gene cluster silencing in Aspergillus nidulans. Mol Microbiol 61(6):1636-45

Bok JW, Chung D, Balajee SA, Marr KA, Andes D, Nielsen KF, Frisvad JC, Kirby KA, Keller NP

Bok JW, et al. (2006) GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence. Infect Immun 74(12):6761-8

Bok JW, Hoffmeister D, Maggio-Hall LA, Murillo R, Glasner JD, Keller NP

Bok JW, et al. (2006) Genomic mining for Aspergillus natural products. Chem Biol 13(1):31-7

Tsitsigiannis DI, Bok JW, Andes D, Nielsen KF, Frisvad JC, Keller NP

Tsitsigiannis DI, et al. (2005) Aspergillus cyclooxygenase-like enzymes are associated with prostaglandin production and virulence. Infect Immun 73(8):4548-59

Bok JW, Balajee SA, Marr KA, Andes D, Nielsen KF, Frisvad JC, Keller NP

Bok JW, et al. (2005) LaeA, a regulator of morphogenetic fungal virulence factors. Eukaryot Cell 4(9):1574-82

Calvo AM, Bok J, Brooks W, Keller NP

Calvo AM, et al. (2004) veA is required for toxin and sclerotial production in Aspergillus parasiticus. Appl Environ Microbiol 70(8):4733-9

Bok JW, Keller NP

Bok JW and Keller NP (2004) LaeA, a regulator of secondary metabolism in Aspergillus spp. Eukaryot Cell 3(2):527-35

Jin Y, Bok JW, Guzman-de-Pena D, Keller NP

Jin Y, et al. (2002) Requirement of spermidine for developmental transitions in Aspergillus nidulans. Mol Microbiol 46(3):801-12

Calvo AM, Wilson RA, Bok JW, Keller NP

Calvo AM, et al. (2002) Relationship between secondary metabolism and fungal development. Microbiol Mol Biol Rev 66(3):447-59, table of contents

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To cite AspGD, please use the following reference: Cerqueira GC, Arnaud MB, Inglis DO, Skrzypek MS, Binkley G, Simison M, Miyasato SR, Binkley J, Orvis J, Shah P, Wymore F, Sherlock G, Wortman JR (2014). The Aspergillus Genome Database: multispecies curation and incorporation of RNA-Seq data to improve structural gene annotations. Nucleic Acids Res 42 (1); D705-10; see How to cite AspGD.