AspGD Curated Papers

Author(s)	Citation
Mulvihill ED, Moloney NM, Owens RA, Dolan SK, Russell L, Doyle S	*Mulvihill ED, et al.* (2017)** Functional Investigation of Iron-Responsive Microsomal Proteins, including MirC, in Aspergillus fumigatus. Front Microbiol 8:418
Dolan SK, Bock T, Hering V, Owens RA, Jones GW, Blankenfeldt W, Doyle S	*Dolan SK, et al.* (2017)** Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus. Open Biol 7(2)
Smith EB, Dolan SK, Fitzpatrick DA, Doyle S, Jones GW	*Smith EB, et al.* (2016)** Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity. Microb Cell 3(3):120-125
Sheridan KJ, Lechner BE, Keeffe GO, Keller MA, Werner ER, Lindner H, Jones GW, Haas H, Doyle S	*Sheridan KJ, et al.* (2016)** Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus. Sci Rep 6:35306
Manzanares-Miralles L, Sarikaya-Bayram O, Smith EB, Dolan SK, Bayram O, Jones GW, Doyle S	*Manzanares-Miralles L, et al.* (2016)** Quantitative proteomics reveals the mechanism and consequence of gliotoxin-mediated dysregulation of the methionine cycle in Aspergillus niger. J Proteomics 131:149-62
Winkelstroter LK, Dolan SK, Dos Reis TF, Bom VL, de Castro PA, Hagiwara D, Alowni R, Jones GW, Doyle S, Brown NA, Goldman GH	*Winkelstroter LK, et al.* (2015)** Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus. G3 (Bethesda) 5(7):1525-39
Owens RA, O'Keeffe G, Smith EB, Dolan SK, Hammel S, Sheridan KJ, Fitzpatrick DA, Keane TM, Jones GW, Doyle S	*Owens RA, et al.* (2015)** Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus. Eukaryot Cell 14(9):941-57
Owens RA, Hammel S, Sheridan KJ, Jones GW, Doyle S	*Owens RA, et al.* (2014)** A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus. PLoS One 9(9):e106942
O Keeffe G, Hammel S, Owens RA, Keane TM, Fitzpatrick DA, Jones GW, Doyle S	*O'Keeffe G, et al.* (2014)** RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus. BMC Genomics 15:894
O'Keeffe G, Jochl C, Kavanagh K, Doyle S	*O'Keeffe G, et al.* (2013)** Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bgamma deletion in Aspergillus fumigatus. Protein Sci 22(11):1612-22
O'Hanlon KA, Gallagher L, Schrettl M, Jochl C, Kavanagh K, Larsen TO, Doyle S	*O'Hanlon KA, et al.* (2012)** Nonribosomal peptide synthetase genes pesL and pes1 are essential for Fumigaclavine C production in Aspergillus fumigatus. Appl Environ Microbiol 78(9):3166-76
O'Hanlon KA, Margison GP, Hatch A, Fitzpatrick DA, Owens RA, Doyle S, Jones GW	*O'Hanlon KA, et al.* (2012)** Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus. Nucleic Acids Res 40(16):7806-20
Gallagher L, Owens RA, Dolan SK, O'Keeffe G, Schrettl M, Kavanagh K, Jones GW, Doyle S	*Gallagher L, et al.* (2012)** The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis. Eukaryot Cell 11(10):1226-38
Carberry S, Molloy E, Hammel S, O'Keeffe G, Jones GW, Kavanagh K, Doyle S	*Carberry S, et al.* (2012)** Gliotoxin effects on fungal growth: mechanisms and exploitation. Fungal Genet Biol 49(4):302-12
O'Hanlon KA, Cairns T, Stack D, Schrettl M, Bignell EM, Kavanagh K, Miggin SM, O'Keeffe G, Larsen TO, Doyle S	*O'Hanlon KA, et al.* (2011)** Targeted disruption of nonribosomal peptide synthetase pes3 augments the virulence of Aspergillus fumigatus. Infect Immun 79(10):3978-92
Davis C, Carberry S, Schrettl M, Singh I, Stephens JC, Barry SM, Kavanagh K, Challis GL, Brougham D, Doyle S	*Davis C, et al.* (2011)** The role of glutathione S-transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus. Chem Biol 18(4):542-52
Davis C, Gordon N, Murphy S, Singh I, Kavanagh K, Carberry S, Doyle S	*Davis C, et al.* (2011)** Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Anal Bioanal Chem 401(8):2519-29
Schrettl M, Carberry S, Kavanagh K, Haas H, Jones GW, O'Brien J, Nolan A, Stephens J, Fenelon O, Doyle S	*Schrettl M, et al.* (2010)** Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin. PLoS Pathog 6(6):e1000952
Stack D, Frizzell A, Tomkins K, Doyle S	*Stack D, et al.* (2009)** Solid phase 4'-phosphopantetheinylation: fungal thiolation domains are targets for chemoenzymatic modification. Bioconjug Chem 20(8):1514-22
Vickers I, Reeves EP, Kavanagh KA, Doyle S	*Vickers I, et al.* (2007)** Isolation, activity and immunological characterisation of a secreted aspartic protease, CtsD, from Aspergillus fumigatus. Protein Expr Purif 53(1):216-24
Stack D, Neville C, Doyle S	*Stack D, et al.* (2007)** Nonribosomal peptide synthesis in Aspergillus fumigatus and other fungi. Microbiology 153(Pt 5):1297-306
Reeves EP, Reiber K, Neville C, Scheibner O, Kavanagh K, Doyle S	*Reeves EP, et al.* (2006)** A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus. FEBS J 273(13):3038-53
Carberry S, Neville CM, Kavanagh KA, Doyle S	*Carberry S, et al.* (2006)** Analysis of major intracellular proteins of Aspergillus fumigatus by MALDI mass spectrometry: identification and characterisation of an elongation factor 1B protein with glutathione transferase activity. Biochem Biophys Res Commun 341(4):1096-104
Reiber K, Reeves EP, Neville CM, Winkler R, Gebhardt P, Kavanagh K, Doyle S	*Reiber K, et al.* (2005)** The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron. FEMS Microbiol Lett 248(1):83-91
Neville C, Murphy A, Kavanagh K, Doyle S	*Neville C, et al.* (2005)** A 4'-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus. Chembiochem 6(4):679-85
Burns C, Geraghty R, Neville C, Murphy A, Kavanagh K, Doyle S	*Burns C, et al.* (2005)** Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus. Fungal Genet Biol 42(4):319-27
Reeves EP, Messina CG, Doyle S, Kavanagh K	*Reeves EP, et al.* (2004)** Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella. Mycopathologia 158(1):73-9
Fox M, Gray G, Kavanagh K, Lewis C, Doyle S	*Fox M, et al.* (2004)** Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development. J Microbiol Methods 56(2):221-30

Author(s)

Citation

Mulvihill ED, Moloney NM, Owens RA, Dolan SK, Russell L, Doyle S

Mulvihill ED, et al. (2017) Functional Investigation of Iron-Responsive Microsomal Proteins, including MirC, in Aspergillus fumigatus. Front Microbiol 8:418

Dolan SK, Bock T, Hering V, Owens RA, Jones GW, Blankenfeldt W, Doyle S

Dolan SK, et al. (2017) Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus. Open Biol 7(2)

Smith EB, Dolan SK, Fitzpatrick DA, Doyle S, Jones GW

Smith EB, et al. (2016) Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity. Microb Cell 3(3):120-125

Sheridan KJ, Lechner BE, Keeffe GO, Keller MA, Werner ER, Lindner H, Jones GW, Haas H, Doyle S

Sheridan KJ, et al. (2016) Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus. Sci Rep 6:35306

Manzanares-Miralles L, Sarikaya-Bayram O, Smith EB, Dolan SK, Bayram O, Jones GW, Doyle S

Manzanares-Miralles L, et al. (2016) Quantitative proteomics reveals the mechanism and consequence of gliotoxin-mediated dysregulation of the methionine cycle in Aspergillus niger. J Proteomics 131:149-62

Winkelstroter LK, Dolan SK, Dos Reis TF, Bom VL, de Castro PA, Hagiwara D, Alowni R, Jones GW, Doyle S, Brown NA, Goldman GH

Winkelstroter LK, et al. (2015) Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus. G3 (Bethesda) 5(7):1525-39

Owens RA, O'Keeffe G, Smith EB, Dolan SK, Hammel S, Sheridan KJ, Fitzpatrick DA, Keane TM, Jones GW, Doyle S

Owens RA, et al. (2015) Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus. Eukaryot Cell 14(9):941-57

Owens RA, Hammel S, Sheridan KJ, Jones GW, Doyle S

Owens RA, et al. (2014) A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus. PLoS One 9(9):e106942

O Keeffe G, Hammel S, Owens RA, Keane TM, Fitzpatrick DA, Jones GW, Doyle S

O'Keeffe G, et al. (2014) RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus. BMC Genomics 15:894

O'Keeffe G, Jochl C, Kavanagh K, Doyle S

O'Keeffe G, et al. (2013) Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bgamma deletion in Aspergillus fumigatus. Protein Sci 22(11):1612-22

O'Hanlon KA, Gallagher L, Schrettl M, Jochl C, Kavanagh K, Larsen TO, Doyle S

O'Hanlon KA, et al. (2012) Nonribosomal peptide synthetase genes pesL and pes1 are essential for Fumigaclavine C production in Aspergillus fumigatus. Appl Environ Microbiol 78(9):3166-76

O'Hanlon KA, Margison GP, Hatch A, Fitzpatrick DA, Owens RA, Doyle S, Jones GW

O'Hanlon KA, et al. (2012) Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus. Nucleic Acids Res 40(16):7806-20

Gallagher L, Owens RA, Dolan SK, O'Keeffe G, Schrettl M, Kavanagh K, Jones GW, Doyle S

Gallagher L, et al. (2012) The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis. Eukaryot Cell 11(10):1226-38

Carberry S, Molloy E, Hammel S, O'Keeffe G, Jones GW, Kavanagh K, Doyle S

Carberry S, et al. (2012) Gliotoxin effects on fungal growth: mechanisms and exploitation. Fungal Genet Biol 49(4):302-12

O'Hanlon KA, Cairns T, Stack D, Schrettl M, Bignell EM, Kavanagh K, Miggin SM, O'Keeffe G, Larsen TO, Doyle S

O'Hanlon KA, et al. (2011) Targeted disruption of nonribosomal peptide synthetase pes3 augments the virulence of Aspergillus fumigatus. Infect Immun 79(10):3978-92

Davis C, Carberry S, Schrettl M, Singh I, Stephens JC, Barry SM, Kavanagh K, Challis GL, Brougham D, Doyle S

Davis C, et al. (2011) The role of glutathione S-transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus. Chem Biol 18(4):542-52

Davis C, Gordon N, Murphy S, Singh I, Kavanagh K, Carberry S, Doyle S

Davis C, et al. (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Anal Bioanal Chem 401(8):2519-29

Schrettl M, Carberry S, Kavanagh K, Haas H, Jones GW, O'Brien J, Nolan A, Stephens J, Fenelon O, Doyle S

Schrettl M, et al. (2010) Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin. PLoS Pathog 6(6):e1000952

Stack D, Frizzell A, Tomkins K, Doyle S

Stack D, et al. (2009) Solid phase 4'-phosphopantetheinylation: fungal thiolation domains are targets for chemoenzymatic modification. Bioconjug Chem 20(8):1514-22

Vickers I, Reeves EP, Kavanagh KA, Doyle S

Vickers I, et al. (2007) Isolation, activity and immunological characterisation of a secreted aspartic protease, CtsD, from Aspergillus fumigatus. Protein Expr Purif 53(1):216-24

Stack D, Neville C, Doyle S

Stack D, et al. (2007) Nonribosomal peptide synthesis in Aspergillus fumigatus and other fungi. Microbiology 153(Pt 5):1297-306

Reeves EP, Reiber K, Neville C, Scheibner O, Kavanagh K, Doyle S

Reeves EP, et al. (2006) A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus. FEBS J 273(13):3038-53

Carberry S, Neville CM, Kavanagh KA, Doyle S

Carberry S, et al. (2006) Analysis of major intracellular proteins of Aspergillus fumigatus by MALDI mass spectrometry: identification and characterisation of an elongation factor 1B protein with glutathione transferase activity. Biochem Biophys Res Commun 341(4):1096-104

Reiber K, Reeves EP, Neville CM, Winkler R, Gebhardt P, Kavanagh K, Doyle S

Reiber K, et al. (2005) The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron. FEMS Microbiol Lett 248(1):83-91

Neville C, Murphy A, Kavanagh K, Doyle S

Neville C, et al. (2005) A 4'-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus. Chembiochem 6(4):679-85

Burns C, Geraghty R, Neville C, Murphy A, Kavanagh K, Doyle S

Burns C, et al. (2005) Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus. Fungal Genet Biol 42(4):319-27

Reeves EP, Messina CG, Doyle S, Kavanagh K

Reeves EP, et al. (2004) Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella. Mycopathologia 158(1):73-9

Fox M, Gray G, Kavanagh K, Lewis C, Doyle S

Fox M, et al. (2004) Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development. J Microbiol Methods 56(2):221-30

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To cite AspGD, please use the following reference: Cerqueira GC, Arnaud MB, Inglis DO, Skrzypek MS, Binkley G, Simison M, Miyasato SR, Binkley J, Orvis J, Shah P, Wymore F, Sherlock G, Wortman JR (2014). The Aspergillus Genome Database: multispecies curation and incorporation of RNA-Seq data to improve structural gene annotations. Nucleic Acids Res 42 (1); D705-10; see How to cite AspGD.