AspGD Curated Papers

Author(s)	Citation
Hunter CC, Siebert KS, Downes DJ, Wong KH, Kreutzberger SD, Fraser JA, Clarke DF, Hynes MJ, Davis MA, Todd RB	*Hunter CC, et al.* (2014)** Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA. Eukaryot Cell 13(4):527-38
Downes DJ, Davis MA, Wong KH, Kreutzberger SD, Hynes MJ, Todd RB	*Downes DJ, et al.* (2014)** Dual DNA binding and coactivator functions of Aspergillus nidulans TamA, a Zn(II)2Cys6 transcription factor. Mol Microbiol 92(6):1198-211
Grundlinger M, Yasmin S, Lechner BE, Geley S, Schrettl M, Hynes M, Haas H	*Grundlinger M, et al.* (2013)** Fungal siderophore biosynthesis is partially localized in peroxisomes. Mol Microbiol 88(5):862-75
Suzuki Y, Murray SL, Wong KH, Davis MA, Hynes MJ	*Suzuki Y, et al.* (2012)** Reprogramming of carbon metabolism by the transcriptional activators AcuK and AcuM in Aspergillus nidulans. Mol Microbiol 84(5):942-64
Bugeja HE, Hynes MJ, Andrianopoulos A	*Bugeja HE, et al.* (2012)** AreA controls nitrogen source utilisation during both growth programs of the dimorphic fungus Penicillium marneffei. Fungal Biol 116(1):145-54
Hynes MJ, Murray SL, Andrianopoulos A, Davis MA	*Hynes MJ, et al.* (2011)** Role of carnitine acetyltransferases in acetyl coenzyme A metabolism in Aspergillus nidulans. Eukaryot Cell 10(4):547-55
Reiser K, Davis MA, Hynes MJ	*Reiser K, et al.* (2010)** Aspergillus nidulans contains six possible fatty acyl-CoA synthetases with FaaB being the major synthetase for fatty acid degradation. Arch Microbiol 192(5):373-82
Reiser K, Davis MA, Hynes MJ	*Reiser K, et al.* (2010)** AoxA is a major peroxisomal long chain fatty acyl-CoA oxidase required for beta-oxidation in A. nidulans. Curr Genet 56(2):139-50
Murray SL, Hynes MJ	Murray SL and Hynes MJ (2010) Metabolic and developmental effects resulting from deletion of the citA gene encoding citrate synthase in Aspergillus nidulans. Eukaryot Cell 9(4):656-66
Hynes MJ, Murray SL, Kahn FK	*Hynes MJ, et al.* (2010)** Deletion of the RING-finger peroxin 2 gene in Aspergillus nidulans does not affect meiotic development. FEMS Microbiol Lett 306(1):67-71
Hynes MJ, Murray SL	Hynes MJ and Murray SL (2010) ATP-citrate lyase is required for production of cytosolic acetyl coenzyme A and development in Aspergillus nidulans. Eukaryot Cell 9(7):1039-48
Wong KH, Hynes MJ, Todd RB, Davis MA	*Wong KH, et al.* (2009)** Deletion and overexpression of the Aspergillus nidulans GATA factor AreB reveals unexpected pleiotropy. Microbiology 155(Pt 12):3868-80
Sprote P, Brakhage AA, Hynes MJ	*Sprote P, et al.* (2009)** Contribution of peroxisomes to penicillin biosynthesis in Aspergillus nidulans. Eukaryot Cell 8(3):421-3
Makita T, Katsuyama Y, Tani S, Suzuki H, Kato N, Todd RB, Hynes MJ, Tsukagoshi N, Kato M, Kobayashi T	*Makita T, et al.* (2009)** Inducer-dependent nuclear localization of a Zn(II)(2)Cys(6) transcriptional activator, AmyR, in Aspergillus nidulans. Biosci Biotechnol Biochem 73(2):391-9
Wong KH, Todd RB, Oakley BR, Oakley CE, Hynes MJ, Davis MA	*Wong KH, et al.* (2008)** Sumoylation in Aspergillus nidulans: sumO inactivation, overexpression and live-cell imaging. Fungal Genet Biol 45(5):728-37
Sprote P, Hynes MJ, Hortschansky P, Shelest E, Scharf DH, Wolke SM, Brakhage AA	*Sprote P, et al.* (2008)** Identification of the novel penicillin biosynthesis gene aatB of Aspergillus nidulans and its putative evolutionary relationship to this fungal secondary metabolism gene cluster. Mol Microbiol 70(2):445-61
Hynes MJ, Murray SL, Khew GS, Davis MA	*Hynes MJ, et al.* (2008)** Genetic analysis of the role of peroxisomes in the utilization of acetate and fatty acids in Aspergillus nidulans. Genetics 178(3):1355-69
Wong KH, Hynes MJ, Todd RB, Davis MA	*Wong KH, et al.* (2007)** Transcriptional control of nmrA by the bZIP transcription factor MeaB reveals a new level of nitrogen regulation in Aspergillus nidulans. Mol Microbiol 66(2):534-51
Todd RB, Davis MA, Hynes MJ	*Todd RB, et al.* (2007)** Genetic manipulation of Aspergillus nidulans: meiotic progeny for genetic analysis and strain construction. Nat Protoc 2(4):811-21
Todd RB, Davis MA, Hynes MJ	*Todd RB, et al.* (2007)** Genetic manipulation of Aspergillus nidulans: heterokaryons and diploids for dominance, complementation and haploidization analyses. Nat Protoc 2(4):822-30
Hynes MJ, Szewczyk E, Murray SL, Suzuki Y, Davis MA, Sealy-Lewis HM	*Hynes MJ, et al.* (2007)** Transcriptional control of gluconeogenesis in Aspergillus nidulans. Genetics 176(1):139-50
Todd RB, Hynes MJ, Andrianopoulos A	*Todd RB, et al.* (2006)** The Aspergillus nidulans rcoA gene is required for veA-dependent sexual development. Genetics 174(3):1685-8
Nayak T, Szewczyk E, Oakley CE, Osmani A, Ukil L, Murray SL, Hynes MJ, Osmani SA, Oakley BR	*Nayak T, et al.* (2006)** A versatile and efficient gene-targeting system for Aspergillus nidulans. Genetics 172(3):1557-66
Monahan BJ, Askin MC, Hynes MJ, Davis MA	*Monahan BJ, et al.* (2006)** Differential expression of Aspergillus nidulans ammonium permease genes is regulated by GATA transcription factor AreA. Eukaryot Cell 5(2):226-37
Hynes MJ, Murray SL, Duncan A, Khew GS, Davis MA	*Hynes MJ, et al.* (2006)** Regulatory genes controlling fatty acid catabolism and peroxisomal functions in the filamentous fungus Aspergillus nidulans. Eukaryot Cell 5(5):794-805
Todd RB, Fraser JA, Wong KH, Davis MA, Hynes MJ	*Todd RB, et al.* (2005)** Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export. Eukaryot Cell 4(10):1646-53
Galagan JE, Calvo SE, Cuomo C, Ma LJ, Wortman JR, Batzoglou S, Lee SI, Basturkmen M, Spevak CC, Clutterbuck J, Kapitonov V, Jurka J, Scazzocchio C, Farman M, Butler J, Purcell S, Harris S, Braus GH, Draht O, Busch S, D'Enfert C, Bouchier C, Goldman GH, Bell-Pedersen D, Griffiths-Jones S, Doonan JH, Yu J, Vienken K, Pain A, Freitag M, Selker EU, Archer DB, Penalva MA, Oakley BR, Momany M, Tanaka T, Kumagai T, Asai K, Machida M, Nierman WC, Denning DW, Caddick M, Hynes M, Paoletti M, Fischer R, Miller B, Dyer P, Sachs MS, Osmani SA, Birren BW	*Galagan JE, et al.* (2005)** Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae. Nature 438(7071):1105-15
Davis MA, Askin MC, Hynes MJ	*Davis MA, et al.* (2005)** Amino acid catabolism by an areA-regulated gene encoding an L-amino acid oxidase with broad substrate specificity in Aspergillus nidulans. Appl Environ Microbiol 71(7):3551-5
Polotnianka R, Monahan BJ, Hynes MJ, Davis MA	*Polotnianka R, et al.* (2004)** TamA interacts with LeuB, the homologue of Saccharomyces cerevisiae Leu3p, to regulate gdhA expression in Aspergillus nidulans. Mol Genet Genomics 272(4):452-9
Todd RB, Greenhalgh JR, Hynes MJ, Andrianopoulos A	*Todd RB, et al.* (2003)** TupA, the Penicillium marneffei Tup1p homologue, represses both yeast and spore development. Mol Microbiol 48(1):85-94
Zuber S, Hynes MJ, Andrianopoulos A	*Zuber S, et al.* (2002)** G-protein signaling mediates asexual development at 25 degrees C but has no effect on yeast-like growth at 37 degrees C in the dimorphic fungus Penicillium mameffei. Eukaryot Cell 1(3):440-7
Monahan BJ, Unkles SE, Tsing I T, Kinghorn JR, Hynes MJ, Davis MA	*Monahan BJ, et al.* (2002)** Mutation and functional analysis of the Aspergillus nidulans ammonium permease MeaA and evidence for interaction with itself and MepA. Fungal Genet Biol 36(1):35-46
Monahan BJ, Fraser JA, Hynes MJ, Davis MA	*Monahan BJ, et al.* (2002)** Isolation and characterization of two ammonium permease genes, meaA and mepA, from Aspergillus nidulans. Eukaryot Cell 1(1):85-94
Hynes MJ, Draht OW, Davis MA	*Hynes MJ, et al.* (2002)** Regulation of the acuF gene, encoding phosphoenolpyruvate carboxykinase in the filamentous fungus Aspergillus nidulans. J Bacteriol 184(1):183-90
Fraser JA, Davis MA, Hynes MJ	*Fraser JA, et al.* (2002)** The genes gmdA, encoding an amidase, and bzuA, encoding a cytochrome P450, are required for benzamide utilization in Aspergillus nidulans. Fungal Genet Biol 35(2):135-46
Fraser JA, Davis MA, Hynes MJ	*Fraser JA, et al.* (2002)** A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance. Appl Environ Microbiol 68(6):2802-8
Borneman AR, Hynes MJ, Andrianopoulos A	*Borneman AR, et al.* (2002)** A basic helix-loop-helix protein with similarity to the fungal morphological regulators, Phd1p, Efg1p and StuA, controls conidiation but not dimorphic growth in Penicillium marneffei. Mol Microbiol 44(3):621-31
Tanaka A, Kamei K, Tanoue S, Papagiannopoulos P, Steidl S, Brakhage AA, Davis MA, Hynes MJ, Kato M, Kobayashi T, Tsukagoshi N	*Tanaka A, et al.* (2001)** AoHapB, AoHapC and AoHapE, subunits of the Aspergillus oryzae CCAAT-binding complex, are functionally interchangeable with the corresponding subunits in Aspergillus nidulans. Curr Genet 39(3):175-82
Szewczyk E, Andrianopoulos A, Davis MA, Hynes MJ	*Szewczyk E, et al.* (2001)** A single gene produces mitochondrial, cytoplasmic, and peroxisomal NADP-dependent isocitrate dehydrogenase in Aspergillus nidulans. J Biol Chem 276(40):37722-9
Steidl S, Hynes MJ, Brakhage AA	*Steidl S, et al.* (2001)** The Aspergillus nidulans multimeric CCAAT binding complex AnCF is negatively autoregulated via its hapB subunit gene. J Mol Biol 306(4):643-53
Small AJ, Todd RB, Zanker MC, Delimitrou S, Hynes MJ, Davis MA	*Small AJ, et al.* (2001)** Functional analysis of TamA, a coactivator of nitrogen-regulated gene expression in Aspergillus nidulans. Mol Genet Genomics 265(4):636-46
Margelis S, D'Souza C, Small AJ, Hynes MJ, Adams TH, Davis MA	*Margelis S, et al.* (2001)** Role of glutamine synthetase in nitrogen metabolite repression in Aspergillus nidulans. J Bacteriol 183(20):5826-33
Fraser JA, Davis MA, Hynes MJ	*Fraser JA, et al.* (2001)** The formamidase gene of Aspergillus nidulans: regulation by nitrogen metabolite repression and transcriptional interference by an overlapping upstream gene. Genetics 157(1):119-31
Boyce KJ, Hynes MJ, Andrianopoulos A	*Boyce KJ, et al.* (2001)** The CDC42 homolog of the dimorphic fungus Penicillium marneffei is required for correct cell polarization during growth but not development. J Bacteriol 183(11):3447-57
Borneman AR, Hynes MJ, Andrianopoulos A	*Borneman AR, et al.* (2001)** An STE12 homolog from the asexual, dimorphic fungus Penicillium marneffei complements the defect in sexual development of an Aspergillus nidulans steA mutant. Genetics 157(3):1003-14
Tanaka A, Kato M, Hashimoto H, Kamei K, Naruse F, Papagiannopoulos P, Davis MA, Hynes MJ, Kobayashi T, Tsukagoshi N	*Tanaka A, et al.* (2000)** An Aspergillus oryzae CCAAT-binding protein, AoCP, is involved in the high-level expression of the Taka-amylase A gene. Curr Genet 37(6):380-7
Borneman AR, Hynes MJ, Andrianopoulos A	*Borneman AR, et al.* (2000)** The abaA homologue of Penicillium marneffei participates in two developmental programmes: conidiation and dimorphic growth. Mol Microbiol 38(5):1034-47
Steidl S, Papagiannopoulos P, Litzka O, Andrianopoulos A, Davis MA, Brakhage AA, Hynes MJ	*Steidl S, et al.* (1999)** AnCF, the CCAAT binding complex of Aspergillus nidulans, contains products of the hapB, hapC, and hapE genes and is required for activation by the pathway-specific regulatory gene amdR. Mol Cell Biol 19(1):99-106
Small AJ, Hynes MJ, Davis MA	*Small AJ, et al.* (1999)** The TamA protein fused to a DNA-binding domain can recruit AreA, the major nitrogen regulatory protein, to activate gene expression in Aspergillus nidulans. Genetics 153(1):95-105
Narendja FM, Davis MA, Hynes MJ	*Narendja FM, et al.* (1999)** AnCF, the CCAAT binding complex of Aspergillus nidulans, is essential for the formation of a DNase I-hypersensitive site in the 5' region of the amdS gene. Mol Cell Biol 19(10):6523-31
Macheda ML, Hynes MJ, Davis MA	*Macheda ML, et al.* (1999)** The Aspergillus nidulans gltA gene encoding glutamate synthase is required for ammonium assimilation in the absence of NADP-glutamate dehydrogenase. Curr Genet 34(6):467-71
Brakhage AA, Andrianopoulos A, Kato M, Steidl S, Davis MA, Tsukagoshi N, Hynes MJ	*Brakhage AA, et al.* (1999)** HAP-Like CCAAT-binding complexes in filamentous fungi: implications for biotechnology. Fungal Genet Biol 27(2-3):243-52
Todd RB, Andrianopoulos A, Davis MA, Hynes MJ	*Todd RB, et al.* (1998)** FacB, the Aspergillus nidulans activator of acetate utilization genes, binds dissimilar DNA sequences. EMBO J 17(7):2042-54
Stemple CJ, Davis MA, Hynes MJ	*Stemple CJ, et al.* (1998)** The facC gene of Aspergillus nidulans encodes an acetate-inducible carnitine acetyltransferase. J Bacteriol 180(23):6242-51
Litzka O, Papagiannopolous P, Davis MA, Hynes MJ, Brakhage AA	*Litzka O, et al.* (1998)** The penicillin regulator PENR1 of Aspergillus nidulans is a HAP-like transcriptional complex. Eur J Biochem 251(3):758-67
Kato M, Aoyama A, Naruse F, Tateyama Y, Hayashi K, Miyazaki M, Papagiannopoulos P, Davis MA, Hynes MJ, Kobayashi T, Tsukagoshi N	*Kato M, et al.* (1998)** The Aspergillus nidulans CCAAT-binding factor AnCP/AnCF is a heteromeric protein analogous to the HAP complex of Saccharomyces cerevisiae. Mol Gen Genet 257(4):404-11
Christensen T, Hynes MJ, Davis MA	*Christensen T, et al.* (1998)** Role of the regulatory gene areA of Aspergillus oryzae in nitrogen metabolism. Appl Environ Microbiol 64(9):3232-7
Andrianopoulos A, Kourambas S, Sharp JA, Davis MA, Hynes MJ	*Andrianopoulos A, et al.* (1998)** Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression. J Bacteriol 180(7):1973-7
Todd RB, Murphy RL, Martin HM, Sharp JA, Davis MA, Katz ME, Hynes MJ	*Todd RB, et al.* (1997)** The acetate regulatory gene facB of Aspergillus nidulans encodes a Zn(II)2Cys6 transcriptional activator. Mol Gen Genet 254(5):495-504
Todd RB, Kelly JM, Davis MA, Hynes MJ	*Todd RB, et al.* (1997)** Molecular characterization of mutants of the acetate regulatory gene facB of Aspergillus nidulans. Fungal Genet Biol 22(2):92-102
Shroff RA, O'Connor SM, Hynes MJ, Lockington RA, Kelly JM	*Shroff RA, et al.* (1997)** Null alleles of creA, the regulator of carbon catabolite repression in Aspergillus nidulans. Fungal Genet Biol 22(1):28-38
Murphy RL, Andrianopoulos A, Davis MA, Hynes MJ	*Murphy RL, et al.* (1997)** Identification of amdX, a new Cys-2-His-2 (C2H2) zinc-finger gene involved in the regulation of the amdS gene of Aspergillus nidulans. Mol Microbiol 23(3):591-602
Straffon MJ, Hynes MJ, Davis MA	*Straffon MJ, et al.* (1996)** Characterization of the ugatA gene of Ustilago maydis, isolated by homology to the gatA gene of Aspergillus nidulans. Curr Genet 29(4):360-9
Papagiannopoulos P, Andrianopoulos A, Sharp JA, Davis MA, Hynes MJ	*Papagiannopoulos P, et al.* (1996)** The hapC gene of Aspergillus nidulans is involved in the expression of CCAAT-containing promoters. Mol Gen Genet 251(4):412-21
Davis MA, Small AJ, Kourambas S, Hynes MJ	*Davis MA, et al.* (1996)** The tamA gene of Aspergillus nidulans contains a putative zinc cluster motif which is not required for gene function. J Bacteriol 178(11):3406-9
Andrianopoulos A, Brons J, Davis MA, Hynes MJ	*Andrianopoulos A, et al.* (1996)** The amdA regulatory gene of Aspergillus nidulans: characterization of gain-of-function mutations and identification of binding sites for the gene product. Fungal Genet Biol 21(1):50-63
Lints R, Davis MA, Hynes MJ	*Lints R, et al.* (1995)** The positively acting amdA gene of Aspergillus nidulans encodes a protein with two C2H2 zinc-finger motifs. Mol Microbiol 15(5):965-75
Bonnefoy N, Copsey J, Hynes MJ, Davis MA	*Bonnefoy N, et al.* (1995)** Yeast proteins can activate expression through regulatory sequences of the amdS gene of Aspergillus nidulans. Mol Gen Genet 246(2):223-7
Hynes MJ	Hynes MJ (1994) Regulatory circuits of the amdS gene of Aspergillus nidulans. Antonie Van Leeuwenhoek 65(3):179-82
Hynes MJ	Hynes MJ (1994) Regulation of acetamide utilization. Prog Ind Microbiol 29:279-97
Davis MA, Kelly JM, Hynes MJ	*Davis MA, et al.* (1993)** Fungal catabolic gene regulation: molecular genetic analysis of the amdS gene of Aspergillus nidulans. Genetica 90(2-3):133-45
Wang XW, Hynes MJ, Davis MA	*Wang XW, et al.* (1992)** Structural and functional analysis of the amdR regulatory gene of Aspergillus oryzae. Gene 122(1):147-54
Saleeba JA, Cobbett CS, Hynes MJ	*Saleeba JA, et al.* (1992)** Characterization of the amdA-regulated aciA gene of Aspergillus nidulans. Mol Gen Genet 235(2-3):349-58
Richardson IB, Katz ME, Hynes MJ	*Richardson IB, et al.* (1992)** Molecular characterization of the lam locus and sequences involved in regulation by the AmdR protein of Aspergillus nidulans. Mol Cell Biol 12(1):337-46
Parsons LM, Davis MA, Hynes MJ	*Parsons LM, et al.* (1992)** Identification of functional regions of the positively acting regulatory gene amdR from Aspergillus nidulans. Mol Microbiol 6(20):2999-3007
Littlejohn TG, Hynes MJ	Littlejohn TG and Hynes MJ (1992) Analysis of the site of action of the amdR product for regulation of the amdS gene of Aspergillus nidulans. Mol Gen Genet 235(1):81-8
van Heeswijck R, Hynes MJ	van Heeswijck R and Hynes MJ (1991) The amdR product and a CCAAT-binding factor bind to adjacent, possibly overlapping DNA sequences in the promoter region of the Aspergillus nidulans amdS gene. Nucleic Acids Res 19(10):2655-60
Sandeman RA, Hynes MJ, Fincham JR, Connerton IF	*Sandeman RA, et al.* (1991)** Molecular organisation of the malate synthase genes of Aspergillus nidulans and Neurospora crassa. Mol Gen Genet 228(3):445-52
van Heeswijck R, Ristevski S, Hynes M, Hoogenraad N	*van Heeswijck R, et al.* (1990)** Complementation of the Aspergillus nidulans arg B1 mutation by ornithine transcarbamylase cDNA from rat liver. Biochem Biophys Res Commun 168(3):1280-4
Turnbull IF, Smith DR, Sharp PJ, Cobon GS, Hynes MJ	*Turnbull IF, et al.* (1990)** Expression and secretion in Aspergillus nidulans and Aspergillus niger of a cell surface glycoprotein from the cattle tick, Boophilus microplus, by using the fungal amdS promoter system. Appl Environ Microbiol 56(9):2847-52
Katz ME, Saleeba JA, Sapats SI, Hynes MJ	*Katz ME, et al.* (1990)** A mutation affecting amdS expression in Aspergillus nidulans contains a triplication of a cis-acting regulatory sequence. Mol Gen Genet 220(3):373-6
Connerton IF, Fincham JR, Sandeman RA, Hynes MJ	*Connerton IF, et al.* (1990)** Comparison and cross-species expression of the acetyl-CoA synthetase genes of the Ascomycete fungi, Aspergillus nidulans and Neurospora crassa. Mol Microbiol 4(3):451-60
Andrianopoulos A, Hynes MJ	Andrianopoulos A and Hynes MJ (1990) Sequence and functional analysis of the positively acting regulatory gene amdR from Aspergillus nidulans. Mol Cell Biol 10(6):3194-203
Sandeman RA, Hynes MJ	Sandeman RA and Hynes MJ (1989) Isolation of the facA (acetyl-coenzyme A synthetase) and acuE (malate synthase) genes of Aspergillus nidulans. Mol Gen Genet 218(1):87-92
Richardson IB, Hurley SK, Hynes MJ	*Richardson IB, et al.* (1989)** Cloning and molecular characterisation of the amdR controlled gatA gene of Aspergillus nidulans. Mol Gen Genet 217(1):118-25
Katz ME, Hynes MJ	Katz ME and Hynes MJ (1989) Isolation and analysis of the acetate regulatory gene, facB, from Aspergillus nidulans. Mol Cell Biol 9(12):5696-701
Katz ME, Hynes MJ	Katz ME and Hynes MJ (1989) Gene function identified by interspecific transformation. Gene 78(1):167-71
Katz ME, Hynes MJ	Katz ME and Hynes MJ (1989) Characterization of the amdR-controlled lamA and lamB genes of Aspergillus nidulans. Genetics 122(2):331-9
Davis MA, Hynes MJ	Davis MA and Hynes MJ (1989) Regulatory genes in Aspergillus nidulans. Trends Genet 5(1):14-9
Hynes MJ, Corrick CM, Kelly JM, Littlejohn TG	*Hynes MJ, et al.* (1988)** Identification of the sites of action for regulatory genes controlling the amdS gene of Aspergillus nidulans. Mol Cell Biol 8(6):2589-96
Davis MA, Cobbett CS, Hynes MJ	*Davis MA, et al.* (1988)** An amdS-lacZ fusion for studying gene regulation in Aspergillus. Gene 63(2):199-212
Andrianopoulos A, Hynes MJ	Andrianopoulos A and Hynes MJ (1988) Cloning and analysis of the positively acting regulatory gene amdR from Aspergillus nidulans. Mol Cell Biol 8(8):3532-41
Kelly JM, Hynes MJ	Kelly JM and Hynes MJ (1987) Multiple copies of the amdS gene of Aspergillus nidulans cause titration of trans-acting regulatory proteins. Curr Genet 12(1):21-31
Davis MA, Hynes MJ	Davis MA and Hynes MJ (1987) Complementation of areA- regulatory gene mutations of Aspergillus nidulans by the heterologous regulatory gene nit-2 of Neurospora crassa. Proc Natl Acad Sci U S A 84(11):3753-7
Corrick CM, Twomey AP, Hynes MJ	*Corrick CM, et al.* (1987)** The nucleotide sequence of the amdS gene of Aspergillus nidulans and the molecular characterization of 5' mutations. Gene 53(1):63-71
Hynes MJ, Davis MA	Hynes MJ and Davis MA (1986) The amdS gene of Aspergillus nidulans: control by multiple regulatory signals. Bioessays 5(3):123-8
Kelly JM, Hynes MJ	Kelly JM and Hynes MJ (1985) Transformation of Aspergillus niger by the amdS gene of Aspergillus nidulans. EMBO J 4(2):475-9
Atkinson PW, King JA, Hynes MJ	*Atkinson PW, et al.* (1985)** Identification of the aciA gene controlled by the amdA regulatory gene in Aspergillus nidulans. Curr Genet 10(2):133-8
Pateman JA, Doy CH, Olsen JE, Norris U, Creaser EH, Hynes M	*Pateman JA, et al.* (1983)** Regulation of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (AldDH) in Aspergillus nidulans. Proc R Soc Lond B Biol Sci 217(1208):243-64
Hynes MJ, Corrick CM, King JA	*Hynes MJ, et al.* (1983)** Isolation of genomic clones containing the amdS gene of Aspergillus nidulans and their use in the analysis of structural and regulatory mutations. Mol Cell Biol 3(8):1430-9
Polkinghorne MA, Hynes MJ	Polkinghorne MA and Hynes MJ (1982) L-histidine utilization in Aspergillus nidulans. J Bacteriol 149(3):931-40
Kelly JM, Hynes MJ	Kelly JM and Hynes MJ (1982) The regulation of NADP-linked isocitrate dehydrogenase in Aspergillus nidulans. J Gen Microbiol 128(1):23-8
Hynes MJ	Hynes MJ (1982) A cis-dominant mutation in aspergillus nidulans affecting the expression of the amdS gene in the presence of mutations in the unlinked gene, amdA. Genetics 102(2):139-47
Kelly JM, Hynes MJ	Kelly JM and Hynes MJ (1981) The regulation of phosphoenolpyruvate carboxykinase and the NADP-linked malic enzyme in Aspergillus nidulans. J Gen Microbiol 123(2):371-5
Hynes MJ	Hynes MJ (1980) A mutation, adjacent to gene amdS, defining the site of action of positive-control gene amdR in Aspergillus nidulans. J Bacteriol 142(2):400-6
Hynes MJ	Hynes MJ (1979) Fine-structure mapping of the acetamidase structural gene and its controlling region in Aspergillus nidulans. Genetics 91(3):381-92
Hynes MJ	Hynes MJ (1978) Multiple independent control mechanisms affecting the acetamidase of Aspergillus nidulans. Mol Gen Genet 161(1):59-65
Hynes MJ	Hynes MJ (1978) An "up-promotor" mutation affecting the acetamidase of Aspergillus nidulans. Mol Gen Genet 166(1):31-6
Kelly JM, Hynes MJ	Kelly JM and Hynes MJ (1977) Increased and decreased sensitivity to carbon catabolite repression of enzymes of acetate metabolism in mutants of Aspergillus nidulans. Mol Gen Genet 156(1):87-92
Hynes MJ, Kelly JM	Hynes MJ and Kelly JM (1977) Pleiotropic mutants of Aspergillus nidulans altered in carbon metabolism. Mol Gen Genet 150(2):193-204
Hynes MJ	Hynes MJ (1977) Induction of the acetamidase of Aspergillus nidulans by acetate metabolism. J Bacteriol 131(3):770-5
Polya GM, Brownlee AG, Hynes MJ	*Polya GM, et al.* (1975)** Enzymology and genetic regulation of a cyclic nucleotide-binding phosphodiesterase-phosphomonoesterase from Aspergillus nidulans. J Bacteriol 124(2):693-703
Polkinghorne M, Hynes MJ	Polkinghorne M and Hynes MJ (1975) Mutants affecting histidine utilization in Aspergillus nidulans. Genet Res 25(2):119-35
Polkinghorne M, Hynes MJ	Polkinghorne M and Hynes MJ (1975) Effect of L-histidine on the catabolism of nitrogenous compounds in Aspergillus nidulans. J Gen Microbiol 87(1):185-7
Hynes MJ	Hynes MJ (1975) Studies on the role of the areA gene in the regulation of nitrogen catabolism in Aspergillus nidulans. Aust J Biol Sci 28(3):301-13
Hynes MJ	Hynes MJ (1975) Amide utilization in Aspergillus nidulans: evidence for a third amidase enzyme. J Gen Microbiol 91(1):99-109
Hynes MJ	Hynes MJ (1975) A cis-dominant regulatory mutation affecting enzyme induction in the eukaryote Aspergillus nidulans. Nature 253(5488):210-2
Hynes MJ	Hynes MJ (1974) The effects of carbon source on glutamate dehydrogenase activities in Aspergillus nidulans. J Gen Microbiol 81(1):165-70
Hynes MJ	Hynes MJ (1974) Repression of enzymes of nitrogen catabolism by methylammonium and caesium chloride in strains of Aspergillus nidulans insensitive to ammonium repression. Mol Gen Genet 132(2):147-52
Hynes MJ	Hynes MJ (1974) Effects of ammonium, L-glutamate, and L-glutamine on nitrogen catabolism in Aspergillus nidulans. J Bacteriol 120(3):1116-23
Hynes MJ	Hynes MJ (1973) The effect of lack of a carbon source on nitrate-reductase activity in Aspergillus nidulans. J Gen Microbiol 79(1):155-7
Hynes MJ	Hynes MJ (1973) Pleiotropic mutants affecting the control of nitrogen metabolism in Aspergillus nidulans. Mol Gen Genet 125(2):99-107
Hynes MJ	Hynes MJ (1973) Alterations in the control of glutamate uptake in mutants of Aspergillus nidulans. Biochem Biophys Res Commun 54(2):685-9
Dunsmuir P, Hynes MJ	Dunsmuir P and Hynes MJ (1973) Temperature sensitive mutants affecting the activity and regulation of the acetamidase of Aspergillus nidulans. Mol Gen Genet 123(4):333-46
Hynes MJ	Hynes MJ (1972) Mutants with altered glucose repression of amidase enzymes in Aspergillus nidulans. J Bacteriol 111(3):717-22
Hynes MJ, Pateman JA	Hynes MJ and Pateman JA (1970) The use of amides as nitrogen sources by Aspergillus nidulans. J Gen Microbiol 63(3):317-24
Hynes MJ, PATEMAN JA	Hynes MJ and Pateman JA (1970) The genetic analysis of regulation of amidase synthesis in Aspergillus nidulans. II. Mutants resistant to fluoroacetamide. Mol Gen Genet 108(2):107-16
Hynes MJ, PATEMAN JA	Hynes MJ and Pateman JA (1970) The genetic analysis of regulation of amidase synthesis in Aspergillus nidulans. I. Mutants able to utilize acrylamide. Mol Gen Genet 108(2):97-106
Hynes MJ	Hynes MJ (1970) Induction and repression of amidase enzymes in Aspergillus nidulans. J Bacteriol 103(2):482-7

Author(s)

Citation

Hunter CC, Siebert KS, Downes DJ, Wong KH, Kreutzberger SD, Fraser JA, Clarke DF, Hynes MJ, Davis MA, Todd RB

Hunter CC, et al. (2014) Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA. Eukaryot Cell 13(4):527-38

Downes DJ, Davis MA, Wong KH, Kreutzberger SD, Hynes MJ, Todd RB

Downes DJ, et al. (2014) Dual DNA binding and coactivator functions of Aspergillus nidulans TamA, a Zn(II)2Cys6 transcription factor. Mol Microbiol 92(6):1198-211

Grundlinger M, Yasmin S, Lechner BE, Geley S, Schrettl M, Hynes M, Haas H

Grundlinger M, et al. (2013) Fungal siderophore biosynthesis is partially localized in peroxisomes. Mol Microbiol 88(5):862-75

Suzuki Y, Murray SL, Wong KH, Davis MA, Hynes MJ

Suzuki Y, et al. (2012) Reprogramming of carbon metabolism by the transcriptional activators AcuK and AcuM in Aspergillus nidulans. Mol Microbiol 84(5):942-64

Bugeja HE, Hynes MJ, Andrianopoulos A

Bugeja HE, et al. (2012) AreA controls nitrogen source utilisation during both growth programs of the dimorphic fungus Penicillium marneffei. Fungal Biol 116(1):145-54

Hynes MJ, Murray SL, Andrianopoulos A, Davis MA

Hynes MJ, et al. (2011) Role of carnitine acetyltransferases in acetyl coenzyme A metabolism in Aspergillus nidulans. Eukaryot Cell 10(4):547-55

Reiser K, Davis MA, Hynes MJ

Reiser K, et al. (2010) Aspergillus nidulans contains six possible fatty acyl-CoA synthetases with FaaB being the major synthetase for fatty acid degradation. Arch Microbiol 192(5):373-82

Reiser K, Davis MA, Hynes MJ

Reiser K, et al. (2010) AoxA is a major peroxisomal long chain fatty acyl-CoA oxidase required for beta-oxidation in A. nidulans. Curr Genet 56(2):139-50

Murray SL, Hynes MJ

Murray SL and Hynes MJ (2010) Metabolic and developmental effects resulting from deletion of the citA gene encoding citrate synthase in Aspergillus nidulans. Eukaryot Cell 9(4):656-66

Hynes MJ, Murray SL, Kahn FK

Hynes MJ, et al. (2010) Deletion of the RING-finger peroxin 2 gene in Aspergillus nidulans does not affect meiotic development. FEMS Microbiol Lett 306(1):67-71

Hynes MJ, Murray SL

Hynes MJ and Murray SL (2010) ATP-citrate lyase is required for production of cytosolic acetyl coenzyme A and development in Aspergillus nidulans. Eukaryot Cell 9(7):1039-48

Wong KH, Hynes MJ, Todd RB, Davis MA

Wong KH, et al. (2009) Deletion and overexpression of the Aspergillus nidulans GATA factor AreB reveals unexpected pleiotropy. Microbiology 155(Pt 12):3868-80

Sprote P, Brakhage AA, Hynes MJ

Sprote P, et al. (2009) Contribution of peroxisomes to penicillin biosynthesis in Aspergillus nidulans. Eukaryot Cell 8(3):421-3

Makita T, Katsuyama Y, Tani S, Suzuki H, Kato N, Todd RB, Hynes MJ, Tsukagoshi N, Kato M, Kobayashi T

Makita T, et al. (2009) Inducer-dependent nuclear localization of a Zn(II)(2)Cys(6) transcriptional activator, AmyR, in Aspergillus nidulans. Biosci Biotechnol Biochem 73(2):391-9

Wong KH, Todd RB, Oakley BR, Oakley CE, Hynes MJ, Davis MA

Wong KH, et al. (2008) Sumoylation in Aspergillus nidulans: sumO inactivation, overexpression and live-cell imaging. Fungal Genet Biol 45(5):728-37

Sprote P, Hynes MJ, Hortschansky P, Shelest E, Scharf DH, Wolke SM, Brakhage AA

Sprote P, et al. (2008) Identification of the novel penicillin biosynthesis gene aatB of Aspergillus nidulans and its putative evolutionary relationship to this fungal secondary metabolism gene cluster. Mol Microbiol 70(2):445-61

Hynes MJ, Murray SL, Khew GS, Davis MA

Hynes MJ, et al. (2008) Genetic analysis of the role of peroxisomes in the utilization of acetate and fatty acids in Aspergillus nidulans. Genetics 178(3):1355-69

Wong KH, Hynes MJ, Todd RB, Davis MA

Wong KH, et al. (2007) Transcriptional control of nmrA by the bZIP transcription factor MeaB reveals a new level of nitrogen regulation in Aspergillus nidulans. Mol Microbiol 66(2):534-51

Todd RB, Davis MA, Hynes MJ

Todd RB, et al. (2007) Genetic manipulation of Aspergillus nidulans: meiotic progeny for genetic analysis and strain construction. Nat Protoc 2(4):811-21

Todd RB, Davis MA, Hynes MJ

Todd RB, et al. (2007) Genetic manipulation of Aspergillus nidulans: heterokaryons and diploids for dominance, complementation and haploidization analyses. Nat Protoc 2(4):822-30

Hynes MJ, Szewczyk E, Murray SL, Suzuki Y, Davis MA, Sealy-Lewis HM

Hynes MJ, et al. (2007) Transcriptional control of gluconeogenesis in Aspergillus nidulans. Genetics 176(1):139-50

Todd RB, Hynes MJ, Andrianopoulos A

Todd RB, et al. (2006) The Aspergillus nidulans rcoA gene is required for veA-dependent sexual development. Genetics 174(3):1685-8

Nayak T, Szewczyk E, Oakley CE, Osmani A, Ukil L, Murray SL, Hynes MJ, Osmani SA, Oakley BR

Nayak T, et al. (2006) A versatile and efficient gene-targeting system for Aspergillus nidulans. Genetics 172(3):1557-66

Monahan BJ, Askin MC, Hynes MJ, Davis MA

Monahan BJ, et al. (2006) Differential expression of Aspergillus nidulans ammonium permease genes is regulated by GATA transcription factor AreA. Eukaryot Cell 5(2):226-37

Hynes MJ, Murray SL, Duncan A, Khew GS, Davis MA

Hynes MJ, et al. (2006) Regulatory genes controlling fatty acid catabolism and peroxisomal functions in the filamentous fungus Aspergillus nidulans. Eukaryot Cell 5(5):794-805

Todd RB, Fraser JA, Wong KH, Davis MA, Hynes MJ

Todd RB, et al. (2005) Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export. Eukaryot Cell 4(10):1646-53

Galagan JE, Calvo SE, Cuomo C, Ma LJ, Wortman JR, Batzoglou S, Lee SI, Basturkmen M, Spevak CC, Clutterbuck J, Kapitonov V, Jurka J, Scazzocchio C, Farman M, Butler J, Purcell S, Harris S, Braus GH, Draht O, Busch S, D'Enfert C, Bouchier C, Goldman GH, Bell-Pedersen D, Griffiths-Jones S, Doonan JH, Yu J, Vienken K, Pain A, Freitag M, Selker EU, Archer DB, Penalva MA, Oakley BR, Momany M, Tanaka T, Kumagai T, Asai K, Machida M, Nierman WC, Denning DW, Caddick M, Hynes M, Paoletti M, Fischer R, Miller B, Dyer P, Sachs MS, Osmani SA, Birren BW

Galagan JE, et al. (2005) Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae. Nature 438(7071):1105-15

Davis MA, Askin MC, Hynes MJ

Davis MA, et al. (2005) Amino acid catabolism by an areA-regulated gene encoding an L-amino acid oxidase with broad substrate specificity in Aspergillus nidulans. Appl Environ Microbiol 71(7):3551-5

Polotnianka R, Monahan BJ, Hynes MJ, Davis MA

Polotnianka R, et al. (2004) TamA interacts with LeuB, the homologue of Saccharomyces cerevisiae Leu3p, to regulate gdhA expression in Aspergillus nidulans. Mol Genet Genomics 272(4):452-9

Todd RB, Greenhalgh JR, Hynes MJ, Andrianopoulos A

Todd RB, et al. (2003) TupA, the Penicillium marneffei Tup1p homologue, represses both yeast and spore development. Mol Microbiol 48(1):85-94

Zuber S, Hynes MJ, Andrianopoulos A

Zuber S, et al. (2002) G-protein signaling mediates asexual development at 25 degrees C but has no effect on yeast-like growth at 37 degrees C in the dimorphic fungus Penicillium mameffei. Eukaryot Cell 1(3):440-7

Monahan BJ, Unkles SE, Tsing I T, Kinghorn JR, Hynes MJ, Davis MA

Monahan BJ, et al. (2002) Mutation and functional analysis of the Aspergillus nidulans ammonium permease MeaA and evidence for interaction with itself and MepA. Fungal Genet Biol 36(1):35-46

Monahan BJ, Fraser JA, Hynes MJ, Davis MA

Monahan BJ, et al. (2002) Isolation and characterization of two ammonium permease genes, meaA and mepA, from Aspergillus nidulans. Eukaryot Cell 1(1):85-94

Hynes MJ, Draht OW, Davis MA

Hynes MJ, et al. (2002) Regulation of the acuF gene, encoding phosphoenolpyruvate carboxykinase in the filamentous fungus Aspergillus nidulans. J Bacteriol 184(1):183-90

Fraser JA, Davis MA, Hynes MJ

Fraser JA, et al. (2002) The genes gmdA, encoding an amidase, and bzuA, encoding a cytochrome P450, are required for benzamide utilization in Aspergillus nidulans. Fungal Genet Biol 35(2):135-46

Fraser JA, Davis MA, Hynes MJ

Fraser JA, et al. (2002) A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance. Appl Environ Microbiol 68(6):2802-8

Borneman AR, Hynes MJ, Andrianopoulos A

Borneman AR, et al. (2002) A basic helix-loop-helix protein with similarity to the fungal morphological regulators, Phd1p, Efg1p and StuA, controls conidiation but not dimorphic growth in Penicillium marneffei. Mol Microbiol 44(3):621-31

Tanaka A, Kamei K, Tanoue S, Papagiannopoulos P, Steidl S, Brakhage AA, Davis MA, Hynes MJ, Kato M, Kobayashi T, Tsukagoshi N

Tanaka A, et al. (2001) AoHapB, AoHapC and AoHapE, subunits of the Aspergillus oryzae CCAAT-binding complex, are functionally interchangeable with the corresponding subunits in Aspergillus nidulans. Curr Genet 39(3):175-82

Szewczyk E, Andrianopoulos A, Davis MA, Hynes MJ

Szewczyk E, et al. (2001) A single gene produces mitochondrial, cytoplasmic, and peroxisomal NADP-dependent isocitrate dehydrogenase in Aspergillus nidulans. J Biol Chem 276(40):37722-9

Steidl S, Hynes MJ, Brakhage AA

Steidl S, et al. (2001) The Aspergillus nidulans multimeric CCAAT binding complex AnCF is negatively autoregulated via its hapB subunit gene. J Mol Biol 306(4):643-53

Small AJ, Todd RB, Zanker MC, Delimitrou S, Hynes MJ, Davis MA

Small AJ, et al. (2001) Functional analysis of TamA, a coactivator of nitrogen-regulated gene expression in Aspergillus nidulans. Mol Genet Genomics 265(4):636-46

Margelis S, D'Souza C, Small AJ, Hynes MJ, Adams TH, Davis MA

Margelis S, et al. (2001) Role of glutamine synthetase in nitrogen metabolite repression in Aspergillus nidulans. J Bacteriol 183(20):5826-33

Fraser JA, Davis MA, Hynes MJ

Fraser JA, et al. (2001) The formamidase gene of Aspergillus nidulans: regulation by nitrogen metabolite repression and transcriptional interference by an overlapping upstream gene. Genetics 157(1):119-31

Boyce KJ, Hynes MJ, Andrianopoulos A

Boyce KJ, et al. (2001) The CDC42 homolog of the dimorphic fungus Penicillium marneffei is required for correct cell polarization during growth but not development. J Bacteriol 183(11):3447-57

Borneman AR, Hynes MJ, Andrianopoulos A

Borneman AR, et al. (2001) An STE12 homolog from the asexual, dimorphic fungus Penicillium marneffei complements the defect in sexual development of an Aspergillus nidulans steA mutant. Genetics 157(3):1003-14

Tanaka A, Kato M, Hashimoto H, Kamei K, Naruse F, Papagiannopoulos P, Davis MA, Hynes MJ, Kobayashi T, Tsukagoshi N

Tanaka A, et al. (2000) An Aspergillus oryzae CCAAT-binding protein, AoCP, is involved in the high-level expression of the Taka-amylase A gene. Curr Genet 37(6):380-7

Borneman AR, Hynes MJ, Andrianopoulos A

Borneman AR, et al. (2000) The abaA homologue of Penicillium marneffei participates in two developmental programmes: conidiation and dimorphic growth. Mol Microbiol 38(5):1034-47

Steidl S, Papagiannopoulos P, Litzka O, Andrianopoulos A, Davis MA, Brakhage AA, Hynes MJ

Steidl S, et al. (1999) AnCF, the CCAAT binding complex of Aspergillus nidulans, contains products of the hapB, hapC, and hapE genes and is required for activation by the pathway-specific regulatory gene amdR. Mol Cell Biol 19(1):99-106

Small AJ, Hynes MJ, Davis MA

Small AJ, et al. (1999) The TamA protein fused to a DNA-binding domain can recruit AreA, the major nitrogen regulatory protein, to activate gene expression in Aspergillus nidulans. Genetics 153(1):95-105

Narendja FM, Davis MA, Hynes MJ

Narendja FM, et al. (1999) AnCF, the CCAAT binding complex of Aspergillus nidulans, is essential for the formation of a DNase I-hypersensitive site in the 5' region of the amdS gene. Mol Cell Biol 19(10):6523-31

Macheda ML, Hynes MJ, Davis MA

Macheda ML, et al. (1999) The Aspergillus nidulans gltA gene encoding glutamate synthase is required for ammonium assimilation in the absence of NADP-glutamate dehydrogenase. Curr Genet 34(6):467-71

Brakhage AA, Andrianopoulos A, Kato M, Steidl S, Davis MA, Tsukagoshi N, Hynes MJ

Brakhage AA, et al. (1999) HAP-Like CCAAT-binding complexes in filamentous fungi: implications for biotechnology. Fungal Genet Biol 27(2-3):243-52

Todd RB, Andrianopoulos A, Davis MA, Hynes MJ

Todd RB, et al. (1998) FacB, the Aspergillus nidulans activator of acetate utilization genes, binds dissimilar DNA sequences. EMBO J 17(7):2042-54

Stemple CJ, Davis MA, Hynes MJ

Stemple CJ, et al. (1998) The facC gene of Aspergillus nidulans encodes an acetate-inducible carnitine acetyltransferase. J Bacteriol 180(23):6242-51

Litzka O, Papagiannopolous P, Davis MA, Hynes MJ, Brakhage AA

Litzka O, et al. (1998) The penicillin regulator PENR1 of Aspergillus nidulans is a HAP-like transcriptional complex. Eur J Biochem 251(3):758-67

Kato M, Aoyama A, Naruse F, Tateyama Y, Hayashi K, Miyazaki M, Papagiannopoulos P, Davis MA, Hynes MJ, Kobayashi T, Tsukagoshi N

Kato M, et al. (1998) The Aspergillus nidulans CCAAT-binding factor AnCP/AnCF is a heteromeric protein analogous to the HAP complex of Saccharomyces cerevisiae. Mol Gen Genet 257(4):404-11

Christensen T, Hynes MJ, Davis MA

Christensen T, et al. (1998) Role of the regulatory gene areA of Aspergillus oryzae in nitrogen metabolism. Appl Environ Microbiol 64(9):3232-7

Andrianopoulos A, Kourambas S, Sharp JA, Davis MA, Hynes MJ

Andrianopoulos A, et al. (1998) Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression. J Bacteriol 180(7):1973-7

Todd RB, Murphy RL, Martin HM, Sharp JA, Davis MA, Katz ME, Hynes MJ

Todd RB, et al. (1997) The acetate regulatory gene facB of Aspergillus nidulans encodes a Zn(II)2Cys6 transcriptional activator. Mol Gen Genet 254(5):495-504

Todd RB, Kelly JM, Davis MA, Hynes MJ

Todd RB, et al. (1997) Molecular characterization of mutants of the acetate regulatory gene facB of Aspergillus nidulans. Fungal Genet Biol 22(2):92-102

Shroff RA, O'Connor SM, Hynes MJ, Lockington RA, Kelly JM

Shroff RA, et al. (1997) Null alleles of creA, the regulator of carbon catabolite repression in Aspergillus nidulans. Fungal Genet Biol 22(1):28-38

Murphy RL, Andrianopoulos A, Davis MA, Hynes MJ

Murphy RL, et al. (1997) Identification of amdX, a new Cys-2-His-2 (C2H2) zinc-finger gene involved in the regulation of the amdS gene of Aspergillus nidulans. Mol Microbiol 23(3):591-602

Straffon MJ, Hynes MJ, Davis MA

Straffon MJ, et al. (1996) Characterization of the ugatA gene of Ustilago maydis, isolated by homology to the gatA gene of Aspergillus nidulans. Curr Genet 29(4):360-9

Papagiannopoulos P, Andrianopoulos A, Sharp JA, Davis MA, Hynes MJ

Papagiannopoulos P, et al. (1996) The hapC gene of Aspergillus nidulans is involved in the expression of CCAAT-containing promoters. Mol Gen Genet 251(4):412-21

Davis MA, Small AJ, Kourambas S, Hynes MJ

Davis MA, et al. (1996) The tamA gene of Aspergillus nidulans contains a putative zinc cluster motif which is not required for gene function. J Bacteriol 178(11):3406-9

Andrianopoulos A, Brons J, Davis MA, Hynes MJ

Andrianopoulos A, et al. (1996) The amdA regulatory gene of Aspergillus nidulans: characterization of gain-of-function mutations and identification of binding sites for the gene product. Fungal Genet Biol 21(1):50-63

Lints R, Davis MA, Hynes MJ

Lints R, et al. (1995) The positively acting amdA gene of Aspergillus nidulans encodes a protein with two C2H2 zinc-finger motifs. Mol Microbiol 15(5):965-75

Bonnefoy N, Copsey J, Hynes MJ, Davis MA

Bonnefoy N, et al. (1995) Yeast proteins can activate expression through regulatory sequences of the amdS gene of Aspergillus nidulans. Mol Gen Genet 246(2):223-7

Hynes MJ

Hynes MJ (1994) Regulatory circuits of the amdS gene of Aspergillus nidulans. Antonie Van Leeuwenhoek 65(3):179-82

Hynes MJ

Hynes MJ (1994) Regulation of acetamide utilization. Prog Ind Microbiol 29:279-97

Davis MA, Kelly JM, Hynes MJ

Davis MA, et al. (1993) Fungal catabolic gene regulation: molecular genetic analysis of the amdS gene of Aspergillus nidulans. Genetica 90(2-3):133-45

Wang XW, Hynes MJ, Davis MA

Wang XW, et al. (1992) Structural and functional analysis of the amdR regulatory gene of Aspergillus oryzae. Gene 122(1):147-54

Saleeba JA, Cobbett CS, Hynes MJ

Saleeba JA, et al. (1992) Characterization of the amdA-regulated aciA gene of Aspergillus nidulans. Mol Gen Genet 235(2-3):349-58

Richardson IB, Katz ME, Hynes MJ

Richardson IB, et al. (1992) Molecular characterization of the lam locus and sequences involved in regulation by the AmdR protein of Aspergillus nidulans. Mol Cell Biol 12(1):337-46

Parsons LM, Davis MA, Hynes MJ

Parsons LM, et al. (1992) Identification of functional regions of the positively acting regulatory gene amdR from Aspergillus nidulans. Mol Microbiol 6(20):2999-3007

Littlejohn TG, Hynes MJ

Littlejohn TG and Hynes MJ (1992) Analysis of the site of action of the amdR product for regulation of the amdS gene of Aspergillus nidulans. Mol Gen Genet 235(1):81-8

van Heeswijck R, Hynes MJ

van Heeswijck R and Hynes MJ (1991) The amdR product and a CCAAT-binding factor bind to adjacent, possibly overlapping DNA sequences in the promoter region of the Aspergillus nidulans amdS gene. Nucleic Acids Res 19(10):2655-60

Sandeman RA, Hynes MJ, Fincham JR, Connerton IF

Sandeman RA, et al. (1991) Molecular organisation of the malate synthase genes of Aspergillus nidulans and Neurospora crassa. Mol Gen Genet 228(3):445-52

van Heeswijck R, Ristevski S, Hynes M, Hoogenraad N

van Heeswijck R, et al. (1990) Complementation of the Aspergillus nidulans arg B1 mutation by ornithine transcarbamylase cDNA from rat liver. Biochem Biophys Res Commun 168(3):1280-4

Turnbull IF, Smith DR, Sharp PJ, Cobon GS, Hynes MJ

Turnbull IF, et al. (1990) Expression and secretion in Aspergillus nidulans and Aspergillus niger of a cell surface glycoprotein from the cattle tick, Boophilus microplus, by using the fungal amdS promoter system. Appl Environ Microbiol 56(9):2847-52

Katz ME, Saleeba JA, Sapats SI, Hynes MJ

Katz ME, et al. (1990) A mutation affecting amdS expression in Aspergillus nidulans contains a triplication of a cis-acting regulatory sequence. Mol Gen Genet 220(3):373-6

Connerton IF, Fincham JR, Sandeman RA, Hynes MJ

Connerton IF, et al. (1990) Comparison and cross-species expression of the acetyl-CoA synthetase genes of the Ascomycete fungi, Aspergillus nidulans and Neurospora crassa. Mol Microbiol 4(3):451-60

Andrianopoulos A, Hynes MJ

Andrianopoulos A and Hynes MJ (1990) Sequence and functional analysis of the positively acting regulatory gene amdR from Aspergillus nidulans. Mol Cell Biol 10(6):3194-203

Sandeman RA, Hynes MJ

Sandeman RA and Hynes MJ (1989) Isolation of the facA (acetyl-coenzyme A synthetase) and acuE (malate synthase) genes of Aspergillus nidulans. Mol Gen Genet 218(1):87-92

Richardson IB, Hurley SK, Hynes MJ

Richardson IB, et al. (1989) Cloning and molecular characterisation of the amdR controlled gatA gene of Aspergillus nidulans. Mol Gen Genet 217(1):118-25

Katz ME, Hynes MJ

Katz ME and Hynes MJ (1989) Isolation and analysis of the acetate regulatory gene, facB, from Aspergillus nidulans. Mol Cell Biol 9(12):5696-701

Katz ME, Hynes MJ

Katz ME and Hynes MJ (1989) Gene function identified by interspecific transformation. Gene 78(1):167-71

Katz ME, Hynes MJ

Katz ME and Hynes MJ (1989) Characterization of the amdR-controlled lamA and lamB genes of Aspergillus nidulans. Genetics 122(2):331-9

Davis MA, Hynes MJ

Davis MA and Hynes MJ (1989) Regulatory genes in Aspergillus nidulans. Trends Genet 5(1):14-9

Hynes MJ, Corrick CM, Kelly JM, Littlejohn TG

Hynes MJ, et al. (1988) Identification of the sites of action for regulatory genes controlling the amdS gene of Aspergillus nidulans. Mol Cell Biol 8(6):2589-96

Davis MA, Cobbett CS, Hynes MJ

Davis MA, et al. (1988) An amdS-lacZ fusion for studying gene regulation in Aspergillus. Gene 63(2):199-212

Andrianopoulos A, Hynes MJ

Andrianopoulos A and Hynes MJ (1988) Cloning and analysis of the positively acting regulatory gene amdR from Aspergillus nidulans. Mol Cell Biol 8(8):3532-41

Kelly JM, Hynes MJ

Kelly JM and Hynes MJ (1987) Multiple copies of the amdS gene of Aspergillus nidulans cause titration of trans-acting regulatory proteins. Curr Genet 12(1):21-31

Davis MA, Hynes MJ

Davis MA and Hynes MJ (1987) Complementation of areA- regulatory gene mutations of Aspergillus nidulans by the heterologous regulatory gene nit-2 of Neurospora crassa. Proc Natl Acad Sci U S A 84(11):3753-7

Corrick CM, Twomey AP, Hynes MJ

Corrick CM, et al. (1987) The nucleotide sequence of the amdS gene of Aspergillus nidulans and the molecular characterization of 5' mutations. Gene 53(1):63-71

Hynes MJ, Davis MA

Hynes MJ and Davis MA (1986) The amdS gene of Aspergillus nidulans: control by multiple regulatory signals. Bioessays 5(3):123-8

Kelly JM, Hynes MJ

Kelly JM and Hynes MJ (1985) Transformation of Aspergillus niger by the amdS gene of Aspergillus nidulans. EMBO J 4(2):475-9

Atkinson PW, King JA, Hynes MJ

Atkinson PW, et al. (1985) Identification of the aciA gene controlled by the amdA regulatory gene in Aspergillus nidulans. Curr Genet 10(2):133-8

Pateman JA, Doy CH, Olsen JE, Norris U, Creaser EH, Hynes M

Pateman JA, et al. (1983) Regulation of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (AldDH) in Aspergillus nidulans. Proc R Soc Lond B Biol Sci 217(1208):243-64

Hynes MJ, Corrick CM, King JA

Hynes MJ, et al. (1983) Isolation of genomic clones containing the amdS gene of Aspergillus nidulans and their use in the analysis of structural and regulatory mutations. Mol Cell Biol 3(8):1430-9

Polkinghorne MA, Hynes MJ

Polkinghorne MA and Hynes MJ (1982) L-histidine utilization in Aspergillus nidulans. J Bacteriol 149(3):931-40

Kelly JM, Hynes MJ

Kelly JM and Hynes MJ (1982) The regulation of NADP-linked isocitrate dehydrogenase in Aspergillus nidulans. J Gen Microbiol 128(1):23-8

Hynes MJ

Hynes MJ (1982) A cis-dominant mutation in aspergillus nidulans affecting the expression of the amdS gene in the presence of mutations in the unlinked gene, amdA. Genetics 102(2):139-47

Kelly JM, Hynes MJ

Kelly JM and Hynes MJ (1981) The regulation of phosphoenolpyruvate carboxykinase and the NADP-linked malic enzyme in Aspergillus nidulans. J Gen Microbiol 123(2):371-5

Hynes MJ

Hynes MJ (1980) A mutation, adjacent to gene amdS, defining the site of action of positive-control gene amdR in Aspergillus nidulans. J Bacteriol 142(2):400-6

Hynes MJ

Hynes MJ (1979) Fine-structure mapping of the acetamidase structural gene and its controlling region in Aspergillus nidulans. Genetics 91(3):381-92

Hynes MJ

Hynes MJ (1978) Multiple independent control mechanisms affecting the acetamidase of Aspergillus nidulans. Mol Gen Genet 161(1):59-65

Hynes MJ

Hynes MJ (1978) An "up-promotor" mutation affecting the acetamidase of Aspergillus nidulans. Mol Gen Genet 166(1):31-6

Kelly JM, Hynes MJ

Kelly JM and Hynes MJ (1977) Increased and decreased sensitivity to carbon catabolite repression of enzymes of acetate metabolism in mutants of Aspergillus nidulans. Mol Gen Genet 156(1):87-92

Hynes MJ, Kelly JM

Hynes MJ and Kelly JM (1977) Pleiotropic mutants of Aspergillus nidulans altered in carbon metabolism. Mol Gen Genet 150(2):193-204

Hynes MJ

Hynes MJ (1977) Induction of the acetamidase of Aspergillus nidulans by acetate metabolism. J Bacteriol 131(3):770-5

Polya GM, Brownlee AG, Hynes MJ

Polya GM, et al. (1975) Enzymology and genetic regulation of a cyclic nucleotide-binding phosphodiesterase-phosphomonoesterase from Aspergillus nidulans. J Bacteriol 124(2):693-703

Polkinghorne M, Hynes MJ

Polkinghorne M and Hynes MJ (1975) Mutants affecting histidine utilization in Aspergillus nidulans. Genet Res 25(2):119-35

Polkinghorne M, Hynes MJ

Polkinghorne M and Hynes MJ (1975) Effect of L-histidine on the catabolism of nitrogenous compounds in Aspergillus nidulans. J Gen Microbiol 87(1):185-7

Hynes MJ

Hynes MJ (1975) Studies on the role of the areA gene in the regulation of nitrogen catabolism in Aspergillus nidulans. Aust J Biol Sci 28(3):301-13

Hynes MJ

Hynes MJ (1975) Amide utilization in Aspergillus nidulans: evidence for a third amidase enzyme. J Gen Microbiol 91(1):99-109

Hynes MJ

Hynes MJ (1975) A cis-dominant regulatory mutation affecting enzyme induction in the eukaryote Aspergillus nidulans. Nature 253(5488):210-2

Hynes MJ

Hynes MJ (1974) The effects of carbon source on glutamate dehydrogenase activities in Aspergillus nidulans. J Gen Microbiol 81(1):165-70

Hynes MJ

Hynes MJ (1974) Repression of enzymes of nitrogen catabolism by methylammonium and caesium chloride in strains of Aspergillus nidulans insensitive to ammonium repression. Mol Gen Genet 132(2):147-52

Hynes MJ

Hynes MJ (1974) Effects of ammonium, L-glutamate, and L-glutamine on nitrogen catabolism in Aspergillus nidulans. J Bacteriol 120(3):1116-23

Hynes MJ

Hynes MJ (1973) The effect of lack of a carbon source on nitrate-reductase activity in Aspergillus nidulans. J Gen Microbiol 79(1):155-7

Hynes MJ

Hynes MJ (1973) Pleiotropic mutants affecting the control of nitrogen metabolism in Aspergillus nidulans. Mol Gen Genet 125(2):99-107

Hynes MJ

Hynes MJ (1973) Alterations in the control of glutamate uptake in mutants of Aspergillus nidulans. Biochem Biophys Res Commun 54(2):685-9

Dunsmuir P, Hynes MJ

Dunsmuir P and Hynes MJ (1973) Temperature sensitive mutants affecting the activity and regulation of the acetamidase of Aspergillus nidulans. Mol Gen Genet 123(4):333-46

Hynes MJ

Hynes MJ (1972) Mutants with altered glucose repression of amidase enzymes in Aspergillus nidulans. J Bacteriol 111(3):717-22

Hynes MJ, Pateman JA

Hynes MJ and Pateman JA (1970) The use of amides as nitrogen sources by Aspergillus nidulans. J Gen Microbiol 63(3):317-24

Hynes MJ, PATEMAN JA

Hynes MJ and Pateman JA (1970) The genetic analysis of regulation of amidase synthesis in Aspergillus nidulans. II. Mutants resistant to fluoroacetamide. Mol Gen Genet 108(2):107-16

Hynes MJ, PATEMAN JA

Hynes MJ and Pateman JA (1970) The genetic analysis of regulation of amidase synthesis in Aspergillus nidulans. I. Mutants able to utilize acrylamide. Mol Gen Genet 108(2):97-106

Hynes MJ

Hynes MJ (1970) Induction and repression of amidase enzymes in Aspergillus nidulans. J Bacteriol 103(2):482-7

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