Index of /download/homology/best_hits

 Name                                                Last modified      Size  Description
 Parent Directory                                                         -   
 A_fumigatus_Af293_A_nidulans_FGSC_A4_best_hits.txt  20-Oct-2011 19:50   66K  
 A_fumigatus_Af293_A_niger_CBS_513_88_best_hits.txt  20-Oct-2011 20:45   82K  
 A_fumigatus_Af293_A_oryzae_RIB40_best_hits.txt      17-Nov-2011 20:28   89K  
 A_fumigatus_Af293_S_cerevisiae_best_hits.txt        20-Oct-2011 19:38   83K  
 A_fumigatus_Af293_S_pombe_best_hits.txt             01-Feb-2012 18:33   72K  
 A_nidulans_FGSC_A4_A_fumigatus_Af293_best_hits.txt  20-Oct-2011 19:51   82K  
 A_nidulans_FGSC_A4_A_niger_CBS_513_88_best_hits.txt 20-Oct-2011 20:47   82K  
 A_nidulans_FGSC_A4_A_oryzae_RIB40_best_hits.txt     17-Nov-2011 20:15   96K  
 A_nidulans_FGSC_A4_S_cerevisiae_best_hits.txt       20-Oct-2011 19:39   78K  
 A_nidulans_FGSC_A4_S_pombe_best_hits.txt            01-Feb-2012 18:17   72K  
 A_niger_CBS_513_88_A_fumigatus_Af293_best_hits.txt  20-Oct-2011 20:50  122K  
 A_niger_CBS_513_88_A_nidulans_FGSC_A4_best_hits.txt 20-Oct-2011 19:57  103K  
 A_niger_CBS_513_88_A_oryzae_RIB40_best_hits.txt     17-Nov-2011 20:46  135K  
 A_niger_CBS_513_88_S_cerevisiae_best_hits.txt       20-Oct-2011 19:41  102K  
 A_niger_CBS_513_88_S_pombe_best_hits.txt            03-Feb-2012 17:15   94K  
 A_oryzae_RIB40_A_fumigatus_Af293_best_hits.txt      17-Nov-2011 20:31  154K  
 A_oryzae_RIB40_A_nidulans_FGSC_A4_best_hits.txt     17-Nov-2011 20:15  136K  
 A_oryzae_RIB40_A_niger_CBS_513_88_best_hits.txt     17-Nov-2011 20:50  158K  
 A_oryzae_RIB40_S_cerevisiae_best_hits.txt           18-Nov-2011 02:55  117K  
 A_oryzae_RIB40_S_pombe_best_hits.txt                02-Feb-2012 17:43  193K  

To determine orthology assignments among Aspergillus species, we used a
Jaccard clustering approach; to determine between Aspergillus species and S. cerevisiae, 
we used InParanoid (http://inparanoid.sbc.su.se/), described in detail at 
http://www.aspgd.org/download/homology/orthologs/.
 
For proteins that did not have an ortholog (in a given species) that meets
the strict criteria we use to define orthology, 
we used BLASTp, using the same parameters as were used by 
InParanoid (-F \"m S\" -M BLOSUM80) with an expectation value (E) of 1e-5, 
to identify the best hit in the protein complement.  

These best hits data are available in the same format as the files containing
the ortholog data. 

The ortholog files are available at
http://www.aspgd.org/download/homology/orthologs/

The best hits data are updated quaterly to ensure that the predictions 
are based on the most up-to-date information.